mangostán

Condiciones de salud que mangostán puede ayudar a apoyar.

• AbscesosCientífico

  Mangosteen pericarp extracts demonstrate potent antibacterial activity against Cutibacterium acnes (formerly P. acnes) and Staphylococcus epidermidis in vitro. A hydrogel patch containing mangosteen pericarp showed bactericidal effects on acne-causing bacteria in a small clinical study. The active compound α-mangostin disrupts bacterial cell membrane integrity. Evidence is largely in vitro and early clinical, with no large RCTs yet.

• HipocondríaCientífico

  Multiple human RCTs confirm oral mangosteen consumption significantly raises plasma antioxidant capacity. A 30-day RCT in 60 healthy adults found 15% higher ORAC-measured antioxidant capacity in the mangosteen group. A single-dose human pharmacokinetic study showed a 60% increase in plasma ORAC within 1 hour of consuming a xanthone-rich beverage, lasting at least 6 hours.

• EccemaCientífico

  Mangosteen xanthones inhibit COX-1, COX-2, NF-κB, and inflammatory cytokine pathways directly relevant to arthritis pathogenesis. A review of mangosteen's anti-inflammatory potency identified arthritis and soft-tissue inflammation among the conditions supported by its xanthone activity. Evidence is primarily preclinical (in vitro and animal), with no dedicated arthritis RCTs in humans.

• EdemaCientífico

  Mangosteen xanthones have been identified as having anti-asthmatic properties in preliminary research, including via histamine H1 receptor blocking activity in isolated smooth muscle preparations. The anti-asthmatic property is cited by Memorial Sloan Kettering from preliminary data. Evidence is limited to laboratory/preclinical studies.

• Adicciones (azúcar o carbohidratos refinados)Científico

  A clinical study in 60 gingivitis patients found that a herbal mouthwash containing mangosteen pericarp extract significantly improved volatile sulfur compound (VSC) levels—the primary chemical cause of halitosis—compared to placebo. MSKCC cites this clinical evidence for halitosis control. The antibacterial activity of xanthones against oral bacteria provides a plausible mechanism.

• Fatiga SuprarrenalCientífico

  A 2018 prospective RCT in 22 obese insulin-resistant women found mangosteen extract (400 mg/day for 26 weeks) reduced HOMA-IR by 53.2% versus 15.2% in controls. γ-Mangostin activates AMPK/PPARγ pathways to lower blood glucose in animal models. A systematic review (2026) identified only two qualifying human studies, both showing promising but preliminary glycemic benefits.

• Fístula anal o fisuraCientífico

  Mangosteen xanthones demonstrate in vitro antifungal activity including against Candida species. Traditional use for thrush (oral candidiasis) is documented in Southeast Asian medicine. The PMC mechanistic review lists Candida glabrata among organisms studied against mangosteen compounds. No human clinical trials for candidiasis have been conducted.

• Válvula IleocecalCientífico

  Clinical RCTs using a mangosteen/Sphaeranthus indicus combination found significant reductions in total cholesterol in obese subjects. A human prospective cohort study in cardiovascular-risk patients showed reduced LDL oxidation markers. Animal studies consistently demonstrate mangosteen extract lowers total cholesterol and LDL while tending to preserve or increase HDL.

• ApendicitisCientífico

  Multiple human RCTs have shown mangosteen-based beverages reduce C-reactive protein (CRP), a key inflammatory marker. A 30-day RCT in 60 healthy adults found CRP dropped from 2.9 mg/L to 1.6 mg/L (p<0.05) in the mangosteen group. Xanthones inhibit NF-κB, COX-2, and MAPK inflammatory pathways in vitro and in human macrophages.

• IncontinenciaCientífico

  Mangosteen pericarp reduced cognitive impairment and decreased phospho-tau in aging mice and triple-transgenic Alzheimer's model mice. Xanthones inhibit amyloid-beta deposition, tau hyperphosphorylation, and cholinergic dysfunction in AD models. A 24-week RCT in 114 schizophrenia patients examined cognitive outcomes with mangosteen pericarp extract. Evidence is primarily preclinical for Alzheimer's specifically.

• Trastorno por Déficit de AtenciónCientífico

  Mangosteen xanthones have demonstrated antidepressant-related effects in preclinical models by modulating monoamine disturbances. A proof-of-concept RCT protocol was published for bipolar depression. A 24-week RCT in 148 schizophrenia patients tested 1,000 mg/day of mangosteen pericarp extract but did not find significant benefit on overall symptoms. Evidence remains largely preclinical.

• FatigaCientífico

  In vitro studies confirm mangosteen xanthones have antifungal activity. Drugs.com and MSKCC cite antibacterial and antifungal properties among documented biological activities of mangosteen xanthones. Traditional use also includes treatment of thrush and skin fungal conditions with pericarp preparations.

• Bultos en el SenoCientífico

  Multiple small clinical studies have shown mangosteen pericarp preparations improve periodontal parameters. A 4% mangostana gel applied into periodontal pockets showed significant improvement in chronic periodontitis. A herbal mouthwash with pericarp extract reduced volatile sulfur compounds (halitosis-related) and improved plaque and bleeding indices in a 60-person gingivitis study.

• Moretones (prevención)Científico

  Clinical trials using a mangosteen/Sphaeranthus indicus combination (Meratrim) in obese subjects demonstrated significant weight loss (5.1 kg vs 1.3 kg in controls) over 16 weeks. An 8-week study in 40 subjects found mangosteen juice blend reduced BMI. α-Mangostin inhibits pancreatic lipase and fatty acid synthase, reducing fat assimilation.

• JuanetesCientífico

  A human prospective cohort study in high cardiovascular-risk patients (Framingham Score) given 2,520 mg/day G. mangostana extract for 90 days showed significantly reduced MDA (lipid peroxidation) and increased SOD, suggesting anti-atherogenic antioxidant effects. Animal studies demonstrate LDL/triglyceride reduction and foam cell inhibition. Xanthones exhibit antiplatelet, vasorelaxant, and cardioprotective properties in preclinical models.

• Olor de piesCientífico

  A 2018 RCT in 22 obese insulin-resistant women found mangosteen extract (400 mg/day, 26 weeks) reduced HOMA-IR by 53.2% versus 15.2% in controls (p=0.004). γ-Mangostin activates AMPK and PPARγ to enhance glucose uptake and GLUT4 translocation. A 2026 systematic review confirmed this as the strongest human evidence for mangosteen's glycemic effects.

• Dolor de cabeza (tensión)Científico

  Mangosteen xanthones inhibit the key inflammatory pathways of rheumatoid arthritis—NF-κB, COX-2, TNF-α, and IL-1β—in both in vitro and animal models. A review specifically identifies rheumatoid-relevant inflammation as a target. No human RCTs have focused on rheumatoid arthritis, but the anti-inflammatory human trial evidence is contextually relevant.

• DebilidadCientífico

  Clinical RCTs using a mangosteen/Sphaeranthus indicus combination in obese subjects found significant reductions in serum triglycerides. Animal studies consistently show mangosteen extract lowers triglycerides via AMPK activation and pancreatic lipase inhibition. A human prospective study in cardiovascular-risk patients provided supporting biomarker evidence.

• Sarpullido por pañalCientífico

  A placebo-controlled clinical trial in 250 HPV16/18-infected women found fermented mangosteen (28 g/day for 3 months) combined with antiviral therapy normalized inflammatory markers and improved colposcopy outcomes. In vitro studies confirm antiviral xanthone activity. Molecular docking studies suggest xanthones may interact with proteins of multiple viral strains.

• DislocaciónTradicional

  Mangosteen pericarp has been used in Southeast Asian traditional medicine for centuries as a treatment for abdominal pain and gastrointestinal discomfort. This is among the most frequently cited traditional applications. No human clinical trials have specifically evaluated this indication.

• Dolor AbdominalTradicional

  Traditional Southeast Asian medicine documents the use of mangosteen pericarp for treating suppuration (pus-forming infections/abscesses). This is among the historically recorded indications dating back nearly 200 years. The antimicrobial properties of xanthones provide biological plausibility but no clinical trials have been conducted.

• Trastornos AutoinmunesTradicional

  The pericarp of mangosteen has a centuries-long documented traditional use across Southeast Asia for treating diarrhea and dysentery. Infusions and decoctions of the peel are traditionally prepared for gastrointestinal complaints. Clinical trial evidence is absent, and one animal study suggested possible worsening of colitis.

• Parálisis de BellTradicional

  Mangosteen rind and leaves have been used in traditional Southeast Asian medicine to treat eczema and pruritus. This use is documented in multiple ethnobotanical records. The anti-inflammatory and antimicrobial properties of xanthones are mechanistically relevant but no clinical trials for eczema have been conducted.

• Sangrado (interno)Tradicional

  Mangosteen pericarp decoctions have been used as antipyretic traditional medicine in Southeast Asia for at least two centuries. Early records document its use as an anti-fever agent in the region. No human clinical trials have evaluated mangosteen specifically for fever.

• Enfermedad del Hígado GrasoTradicional

  Traditional use of mangosteen pericarp for gastrointestinal conditions including stomach complaints is documented across Southeast Asia. The antimicrobial and anti-inflammatory properties of xanthones are mechanistically relevant to Helicobacter pylori-associated gastritis. No human clinical trials have evaluated mangosteen specifically for gastritis.

• Hernia HiatalTradicional

  Traditional use of mangosteen pericarp for chronic ulcers is well-documented across Southeast Asian cultures, and this is among the oldest recorded medicinal applications of the plant. No human clinical trials have been conducted for gastric or chronic wound ulcers with mangosteen.

• Llagas por DentaduraTradicional

  Traditional medicine records from nearly 200 years ago document mangosteen peel decoctions being used to treat genitourinary disorders including cystitis and urinary tract infections. Bark concentrates were used for GU disorders including gonorrhea. No human clinical trials support this use.

• DifteriaTradicional

  Traditional use of mangosteen pericarp for infected wounds and suppuration is well-documented across Southeast Asian cultures. The rind has historically been applied as an antibacterial agent for wound management and chronic ulcers. Memorial Sloan Kettering notes clinical data for wound healing are lacking despite laboratory antimicrobial evidence.

Sistemas corporales que mangostán puede ayudar a apoyar.

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