marrubio

Condiciones de salud que marrubio puede ayudar a apoyar.

• HipocondríaCientífico

  Multiple in vitro and laboratory studies confirm strong antioxidant activity of M. vulgare extracts, with DPPH radical scavenging of 68.29% and measurable FRAP values. Key phenolic constituents including quercetin, ferulic acid, catechin, and rutin contribute to ROS scavenging. Evidence is laboratory-based; human clinical antioxidant trials have not been conducted.

• HipotensiónCientífico

  Multiple rodent studies demonstrate antihypertensive effects of M. vulgare water extract in spontaneously hypertensive rats, with the diterpene marrubenol characterised as an L-type calcium channel blocker. Effects were comparable in some parameters to the calcium antagonist amlodipine. No human clinical trials for blood pressure have been conducted.

• Fatiga SuprarrenalCientífico

  Multiple animal studies show M. vulgare extracts reduce blood glucose in diabetic rodent models, and one small clinical study in type 2 diabetics found modest reductions in plasma glucose after 21 days of horehound tea. Evidence is preliminary and no large RCTs exist, but the hypoglycaemic signal is consistent across preclinical models and one human trial.

• Válvula IleocecalCientífico

  Animal studies show M. vulgare extracts significantly reduce total cholesterol, LDL, and triglycerides. An in vitro study demonstrated inhibition of human LDL oxidation and enhanced HDL-mediated cholesterol efflux in macrophages. A small human clinical study noted modest reductions in cholesterol. Evidence remains preliminary with limited clinical data.

• ApendicitisCientífico

  Animal and in vitro studies demonstrate that M. vulgare extracts reduce pro-inflammatory markers including TNF-α and myeloperoxidase activity. Flavonoids such as luteolin and quercetin, alongside marrubiin, contribute to COX inhibition and reduced inflammatory mediators. No human clinical trials have been conducted for chronic inflammatory conditions.

• JuanetesCientífico

  Animal studies have demonstrated antiarrhythmic, vasodilatory, and antihypertensive properties of horehound diterpenes, particularly marrubenol acting as an L-type calcium channel blocker. An in vitro study showed M. vulgare extract inhibits human LDL oxidation and enhances HDL-mediated cholesterol efflux. Evidence is exclusively preclinical.

• Envenenamiento QuímicoCientífico

  Animal and in vitro studies consistently document hepatoprotective activity of M. vulgare, linked to its antioxidant phenolic compounds and a novel monoterpene acid. WebMD and Drugs.com list liver complaints among traditional uses, while the PMC pharmacological overview includes hepatoprotective activity among the most investigated properties. No human clinical trials exist.

• Hernia HiatalCientífico

  A 2011 in vivo study demonstrated that M. vulgare methanol extract and isolated marrubiin exhibit gastroprotective and antiulcer activity in rodent models, reducing acid secretion and stimulating protective mucus. Evidence is preclinical only; no human clinical trials for gastric or peptic ulcers have been conducted.

• DifteriaCientífico

  Wound healing activity of M. vulgare is supported by in vitro and animal studies, as well as ethnobotanical documentation from Morocco, Tunisia, and Algeria. A 2017 study demonstrated antioxidant and wound healing properties of leaf extract, and a 2022 PMC study showed accelerated burn wound healing using a horehound-containing ointment. All evidence remains preclinical.

• DislocaciónTradicional

  German Commission E approved horehound for dyspepsia, and the EMA HMPC lists symptomatic relief of minor dyspeptic complaints (bloating, gas) as a traditional use indication. Marrubiin acts as a gastric juice stimulant while the plant's antispasmodic properties address intestinal spasm. No clinical trials for abdominal symptoms as primary endpoints exist.

• AcnéTradicional

  Horehound's bitter compounds, particularly marrubiin, are recognized by the German Commission E and the EMA's HMPC as stimulating gastric juice secretion and appetite via activation of bitter taste receptors. This traditional use has at least 30 years of documented safe use in Europe. No controlled human trials specifically measuring appetite endpoints have been conducted.

• EdemaTradicional

  Horehound has been used traditionally for asthma since ancient times, mentioned by Roman and 19th-century American Eclectic physicians. Its antispasmodic activity on bronchial smooth muscle provides mechanistic plausibility. No controlled clinical trials for asthma have been conducted.

• AlcalosisTradicional

  White horehound (Marrubium vulgare) has been used since antiquity in European herbal medicine as an expectorant and bronchospasmolytic for bronchitis, coughs, and bronchial mucus congestion. Its active compound marrubiin is documented to have expectorant and antispasmodic effects on bronchial smooth muscle. EBSCO's natural medicine database lists it among herbs with traditional support for bronchitis treatment.

• EndometriosisTradicional

  White horehound (Marrubium vulgare) is listed in the EBSCO evidence database among proposed traditional bronchitis treatments. German Commission E approves horehound for non-productive cough and respiratory catarrh. Its diterpene marrubiin stimulates bronchial secretion, acting as a natural expectorant.

• ArritmiaTradicional

  Horehound has been used since ancient Rome as a remedy for colds and catarrh, and is listed in German Commission E monographs as a traditional cold remedy. The EMA HMPC bases its positive opinion on traditional use with at least 30 years of documented safe use within Europe. No placebo-controlled human trials for cold or flu specifically have been conducted.

• Sangrado (interno)Tradicional

  Horehound has a long-standing traditional reputation as a diaphoretic—promoting perspiration to assist in fever management. This use is documented across European, North African, and Middle Eastern herbal traditions. No controlled clinical studies on horehound for fever reduction exist.

• Ojos Inyectados en SangreTradicional

  German Commission E approved horehound as a choleretic, and the EMA/HMPC cites liver and gallbladder complaints among its traditional indications. The active compound marrubiinic acid—formed from marrubiin—demonstrated choleretic activity in rat experiments. Human clinical data are absent.

• Quimioterapia (reducción de efectos secundarios)Tradicional

  Horehound (Marrubium vulgare) has been used in European, North African, and American traditional medicine for respiratory complaints including cough and bronchitis. It is approved by the German Commission E for symptomatic relief of acute bronchitis and cough, classified as an expectorant and bronchosecretolytic herb.

• Manos y Pies FríosTradicional

  Horehound (Marrubium vulgare) is a member of the mint family with a long history in Western herbalism for dry, spasmodic, non-productive coughs and bronchitis. It is classified as a stimulating expectorant and is one of the ingredients in Ricola herbal cough drops. German Commission E recognizes its traditional use and multiple pharmacopeias include it as an expectorant for mucus-related coughs.

• Cuidado del cabello (general)Tradicional

  Horehound has been used traditionally for whooping cough (pertussis) across European, British, and American herbal traditions, owing to its expectorant and antispasmodic properties. The British Pharmacopoeia describes its use as an antispasmodic for whooping cough. No clinical trials in pertussis patients have been conducted.

• Tos (general)Tradicional

  Horehound is one of the oldest documented respiratory remedies, used across European, Egyptian, and Ayurvedic traditions for catarrh, cough, and bronchial congestion associated with seasonal respiratory episodes. The EMA HMPC recognises its traditional use for cough related to upper respiratory tract symptoms. Its inclusion in commercial formulations such as Ricola lozenges reflects ongoing practical use.

• Tos (espasmódica)Tradicional

  Horehound is traditionally used for sinus congestion and catarrh as part of its broader respiratory folk medicine application. Its expectorant and mucolytic properties are proposed to assist in clearing nasal and sinus passages. No clinical studies targeting sinus or nasal outcomes specifically have been conducted.

• Enfermedad de CushingTradicional

  Horehound has been used traditionally since Roman times to soothe sore throats, and it remains an ingredient in commercial throat lozenges. The EMA HMPC bases its positive opinion on traditional use for cough and throat irritation. No human clinical trials for sore throat endpoints have been performed.

• DefensividadTradicional

  Horehound is classified by EMA HMPC and German Commission E as a traditional herbal medicine for relief of cough associated with upper respiratory tract colds. Its expectorant, mucolytic, and mild antispasmodic actions underpin this use. Human clinical trial evidence is absent; the EMA's positive opinion is based on plausibility and documented traditional use for ≥30 years.

• DiarreaTradicional

  Horehound has been used traditionally as a diuretic to promote urine flow and reduce fluid retention. This property is documented in multiple ethnobotanical sources and Western herbal texts. No controlled clinical studies on diuretic activity in humans have been published.

Sistemas corporales que marrubio puede ayudar a apoyar.

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