Evidence supporting the use of: Turmeric
For the health condition: Nephritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Turmeric (Curcuma longa) contains the active compound curcumin, which has been widely studied for its anti-inflammatory and antioxidant properties. The use of turmeric to support kidney health, including in conditions such as nephritis (inflammation of the kidneys), is supported by some preclinical and limited clinical evidence. Animal studies have shown that curcumin can reduce markers of inflammation and oxidative stress in models of nephritis, potentially attenuating kidney damage. For example, curcumin has been found to suppress nuclear factor-kappa B (NF-κB) and reduce levels of pro-inflammatory cytokines, which are implicated in the pathogenesis of nephritis. In addition, curcumin may help reduce fibrosis and proteinuria—key features of chronic kidney disease. However, high-quality human clinical trials are limited. Some small studies and case reports suggest potential benefits, but the evidence is not strong or consistent enough for curcumin/turmeric to be considered a standard therapy for nephritis. Most guidelines do not recommend turmeric as a primary treatment, but it is sometimes used as an adjunctive therapy in traditional and integrative medicine settings. Safety concerns also exist, especially regarding high doses and interactions with medications metabolized by the liver. Overall, while there is scientific rationale and some preliminary evidence, more robust clinical trials are needed to establish efficacy and safety for nephritis.

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Other health conditions supported by turmeric

Abdominal Pain
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Acid Indigestion
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