Evidence supporting the use of: Licorice root
For the health condition: Dyspepsia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Licorice root (Glycyrrhiza glabra) has been used historically in various traditional medicine systems, such as Traditional Chinese Medicine and Ayurveda, to support digestive health and treat dyspepsia (indigestion). Modern scientific research has begun to validate some of these uses. Specifically, deglycyrrhizinated licorice (DGL) is the form most commonly studied for gastrointestinal complaints, including functional dyspepsia.

Clinical trials and observational studies suggest that DGL may help alleviate symptoms of dyspepsia, such as bloating, discomfort, and epigastric pain. The proposed mechanisms include increased production of mucus in the stomach lining, which helps protect against acid and irritants, and potential anti-inflammatory effects. Some randomized controlled trials have demonstrated that DGL can improve symptoms of functional dyspepsia when compared to placebo, though the quality and size of the studies are moderate and more research is needed for definitive conclusions.

While the traditional use of licorice root for digestive issues provides historical context, the current scientific evidence is sufficient to justify its use as a supportive treatment for dyspepsia, but it is not as robust as for some other treatments. Safety should also be considered: whole licorice root (containing glycyrrhizin) can cause side effects like hypertension and hypokalemia if used excessively, so DGL is preferred for long-term or frequent use. Overall, licorice root (especially as DGL) is a scientifically supported option for dyspepsia, but with moderate-quality evidence (3/5) and best used as adjunctive therapy.

More about licorice root
More about Dyspepsia

Other ingredients used for Dyspepsia

cutch
allspice
aloe vera
green chiretta
apple
artichoke
barberry
basil
myrobalan
berry flavor
betel
bilberry
black pepper
blackberry
rice
chamomile
Coptis chinensis
turmeric
curcumin
dandelion
fennel
flavonols
ginger
goldenseal
heartwood
Indian tinospora
licorice root
marshmallow
mustard seed
oregon grape
peppermint oil
phellodendron amurense
plantain
plum fruit
raspberry
slippery elm bark
sphaeranthus indicus
triphala
gastrodia
cardamom
papaya
Indian bael
neem tree
nut grass
alpinia galangal
clerodendrum indicum
ferula assafoetida
hedychium spicatum
anise
tinospora cordifolia
blackboard tree
caesalpinia crista
fumaria parviflora
swertia
peony
boxthorne
yarrow
prickly ash
myrrh
chrysanthemum
dioscorea
fern
hyacinth bean
sweetgums
morinda
trichosanthes
zanthoxylum
wood betony
white oak
indigo leaves
enzymes blend (proprietary)
geranium
Avens
Angelica
acacia
Agrimony
Achyranthes
Abrus
Amomum
Asafoetida
Ajuga
Anserina
Aerva lanata
American Liverleaf
Asam gelugor
Angostura
Alsonia scholaris
Agrimonia pilosa
Asteracea
Ananain
Abuta
Aniseed myrtle
Arisaema
Black Seed
Bai Ji
Bidens pilosa
Blackthorn
Bicarbonate
Blepharis
Belleric myrobalan
Bistort
Butea monosperma
Barleria
Bitter Grass
Bael
Boswellia
Banyan
Bur-Reed
Black Nightshade
Bombax
Bitter principals
Black root
banana
Bergenia
Boerhavia diffusa
Centaury
Cinnamomum
Combretum quadrangulare
Clerodendrum phlomidis
Centaurium erythraea
Citron
Carry Me Seed
Capsaicin
Curcumen
Catechu
Campylandra fimbriata
Colombo
Corktree
Curcuma
Chirata
Costus
Colocynth
Celosia
Dianthrone
Dichrostachys glomerata
Elephant's Head
Embelia
Goldthread
Galangal
Lotus
Little ironweed
Snakeroot (unspecified)

Other health conditions supported by licorice root

Abdominal Pain
Abrasions
Abscesses
Acid Indigestion
Acne
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Addison's Disease
Adenitis
Adrenal Fatigue
Afterbirth Pain
Age Spots
Allergies (respiratory)
Amenorrhea
Anal Fistula or Fissure
Anemia
Appetite (deficient)
Asthma
Autoimmune Disorders
Bronchitis
Canker Sores
Chemotherapy (reducing side effects)
Chicken Pox
Cholera
Chronic Obstructive Pulmonary Disorder
Cirrhosis of the Liver
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colic (adults)
Colic (children)
Colitis
Colon (atonic)
Colon (spastic)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (lymphatic)
Congestion (sinus)
Constipation (adults)
Contagious Diseases
Convalescence
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cramps (menstrual)
Crohn's Disease
Croup
Cushing's Disease
Cytomealovirus
Dyspepsia
Eczema
Emphysema
Endometriosis
Enteritis
Epstein Barr Virus
Estrogen (low)
Fatty Liver Disease
Fever
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Gas and Bloating
Gastritis
Gingivitis
Glands (swollen lymph)
Goiter
Gonorrhea
Gout
Grave's Disease
Hair (loss or thinning)
Hair Care (general)
Halitosis
Hangover
Headache (general)
Headache (sinus)
Headache (tension)
Heart (weakness)
Hemorrhoids
Hepatitis
Hernias
Herpes
Hiatal Hernia
Hiccups
Hot Flashes
Hypotension
Hypothyroid
Impetigo
Indigestion
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Itching
Itching Ears
Jaundice (adults)
Jock Itch
Kidney Infection
Laryngitis
Leaky Gut Syndrome
Leprosy
Lesions
Leucorrhea
Liver Detoxification
Lungs (fluid in)
Lyme Disease
Lymph Nodes or Glands (swollen)
Malaria
Mastitis
Measles
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Metabolic Syndrome
Mononucleosis
Mood Swings
Morning Sickness
Mumps
Nausea and Vomiting
Nephritis
Nervous Exhaustion
Nervousness
Night Sweating
Nocturnal Emission
Oral Surgery
Ovarian Pain
Overacidity
Pertussis
Pleurisy
PMS (general)
Pneumonia
Poison Ivy or Oak
Rashes and Hives
Rosacea
Sore Throat
Ulcers

Products containing licorice root

Nature's Sunshine Adrenal Support
Nature's Sunshine Anti-Gas (Chinese)
Nature's Sunshine Anti-Gas TCM
Nature's Sunshine Bronchial Formula (Ayurvedic)
Nature's Sunshine Breathe Activator TCM (formerly Breathe E-Z)
Nature's Sunshine C-X
Nature's Sunshine Combination CBG Extract
Nature's Sunshine Chinese TCM Positive Pack
Nature's Sunshine Chinese TCM Negative Pack
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Energ-V Capsules
Nature's Sunshine Female Comfort
Nature's Sunshine Gastro Health
Nature's Sunshine Glandular System
Nature's Sunshine Hepatic System
Nature's Sunshine HY-C
Nature's Sunshine HY-C TCM
Nature's Sunshine IF-C
Nature's Sunshine IF-C TCM
Nature's Sunshine Immune System
Nature's Sunshine Kidney Activator TCM
Nature's Sunshine Kidney Activator (Chinese)
Nature's Sunshine LB Extract
Nature's Sunshine Lower Bowel Stimulator (Formerly LBS II)
Nature's Sunshine LBS II
Nature's Sunshine Licorice Root
Nature's Sunshine Licorice Root Extract
Nature's Sunshine Liver Balance (Chinese)
Nature's Sunshine Liver Balance TCM
Nature's Sunshine Lung Support (Chinese)
Nature's Sunshine Lung Support TCM
Nature's Sunshine Magnesium
Nature's Sunshine Master Gland Formula®
Nature's Sunshine Mineral-Chi Tonic (Chinese)
Nature's Sunshine Mood Elevator (Chinese)
Nature's Sunshine Mood Elevator TCM
Nature's Sunshine Nature's Chi TCM
Nature's Sunshine Natural Changes
Nature's Sunshine Pro-Pancreas Formula
Nature's Sunshine PS II
Nature's Sunshine Psyllium Hulls Combo
Nature's Sunshine Red Beet Root Formula
Nature's Sunshine Respiratory System (30 Day Program)
Nature's Sunshine SF
Nature's Sunshine Skeletal Strength
Nature's Sunshine Spleen Activator (Chinese)
Nature's Sunshine Spleen Activator TCM
Nature's Sunshine Stomach Comfort (Chewable)
Nature's Sunshine Stress Relief
Nature's Sunshine Stress Relief TCM
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Tiao He Cleanse
Nature's Sunshine Trigger Immune (Chinese)
Nature's Sunshine Trigger Immune TCM
Nature's Sunshine Ultimate GreenZone
Nature's Sunshine Ultimate Greenzone
Nature's Sunshine VS-C
Nature's Sunshine VS-C
Nature's Sunshine VS-C® TCM
Nature's Sunshine Women's X-Action