Evidence supporting the use of: Mullein
For the health condition: Skin (infections)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Mullein (Verbascum thapsus) has a long history of traditional use for various skin conditions, including infections, wounds, and inflammatory skin issues. Folk medicine practices in Europe and North America have used mullein leaves and flowers topically, often as poultices or infused oils, to help treat minor wounds, burns, and skin infections. The rationale behind this usage is largely based on mullein's perceived anti-inflammatory, soothing, and mild antimicrobial properties, with herbalists historically recommending it for its ability to "draw out" infections and promote healing.
Modern scientific validation of mullein's topical benefits is limited. Laboratory studies have identified certain compounds in mullein, such as saponins, flavonoids, and phenylethanoid glycosides, which may possess mild antimicrobial and anti-inflammatory effects. However, there is a lack of robust clinical trials or well-designed human studies specifically investigating mullein's effectiveness in treating skin infections. Most available evidence is anecdotal or stems from in vitro (test tube) studies showing some activity against bacteria and fungi. Thus, while its use is justified by traditional knowledge and some preliminary laboratory support, there is not enough high-quality scientific evidence to strongly recommend mullein for skin infections.
In summary, the use of mullein for skin infections is primarily supported by tradition, with some weak scientific plausibility, warranting a moderate evidence rating of 2 out of 5.
Other ingredients used for Skin (infections)
AjoeneAloe vera
alpha-pinene
barberry
beeswax
bisabolol
black walnut
chlorophyll
copper
turmeric
echinacea purpurea
goldenseal
heartwood
knotweed
Japanese sophora
lactiplantibacillus plantarum
Lactoperoxidase
Monolaurin
quercetin
Trypsin
vitamin C
Zinc
bentonite
sarsaparilla
Yellow root
Mullein
chickweed
typhonium
paederia foetida
smilax
Rubia cordifolia
privet
goldenrod
Yarrow
juniper berries
sweetgums
oriental arborvitae
sheep's sorrel
queen of the meadow
Wintergreen
camphor oil
Stillingia
White oak
melaleuca alternifolia
10-Undecenoic Acid
15,16-Dihydrotanshinone I
3-Phenyllactic Acid
Akebia
Aquilegia viridiflora
alpha-terpineol
azelaic acid
Ardisia
Agave
Antirrhinum majus
Achyranthes
Alchornea
American Pawpaw
Albizia
asafoetida
Ajuga
aucubin
Aerva lanata
American Liverleaf
Asam gelugor
Allantoin
Aureobasidium pullulans
Alkanet
Alstonia scholaris
Ampelopsis
Acemannan
Allyl isothiocyanate
Abuta
Alkanna
Arisaema
Alantolactone
Artepillin C
babchi
Baliospermum
Baphicacanthus cusia
Black spruce
Blepharis
Boswellic Acid
Bougainvillea
Brazilian peppertree
bisabolene
bael
benzoin
Backhousia citriodora
banyan
Bacillus
burning bush
Bergenia
Casearia esculenta
croton seeds
Clerodendrum phlomidis
citral
California pitcher plant
Cistus
cypress
chaparral
Chondracanthus chamissoi
Cedrus libani
castile soap
Cynodon dactylon
Chiococca alba
cocklebur
Chekiang Fritillary
copaiba oil
citronella
Didymocarpus
daphne
emu oil
Echinodorus
Ficus religiosa
farnesol
fleabane
frankincense
fir
gallic acid
geraniol
genipap
glyceryl caprylate caprate
Galium
geranial
Glycolipids
Glycyrrhetinic acid
Gigartina
Galbanum
golden shower tree
Guazuma ulmifolia
Hypericin
Hemidesmus
Homalomena
Houttuynia
hydroxyquinoline
Hyaluronidase
Immunoglobulin G
Indian nightshade
Indian sarsparilla
Immortelle
Ivy
Jatoba
Kigelia africana
Kachnar
knotgrass
loquat
Lactobacillus plantarum
Ledebouriella
Lilium polyphyllum
Lactococcus rhamnosus
Lophira lanceolata
lupulone
lactic acid
Leptadenia
Lantana camara
Leptospermum scoparium
liverwort
Loranthus
Laminaria
Lysimachia
Labdanum
Mesua
Mountain horopito
Marjoram
Mucilage
Mountain mahogany
Matapalo Tree
Mahonia
Milkweed
Marking Nut Tree
manzanita
Nasturtium
Night jessamine
Oak
Oldenlandia diffusa
purple Tephrosia
Premna
Pepper Bark Tree
Polypodium
Pentatropis capensis
Plumbago zeylanica
Queen's Delight
Rosmanol
Rosa laevigata
Rhododendron
Spilanthes
Silkmoth
Streptomyces
Scoparia dulcis
Shikonin
Spikenard
Snakeroot
Silk protein
Sesquiterpenic Acid
Solanum anguivi
Sarcandra glabra
Semiaquilegia
Soapberry
Sapindus mukorossi
Semecarpus anacardium
Simaruba
Skunkvine
Storax
Stone Root
Smoketree
Terpinen-4-ol
Thymol
Takuna
Veronica
Verbascoside
Wrightia tinctoria
Witch Hazel
Waltheria ovata
Xanthorrhizol
Xanthoparmelia
Yellow-Fruit Nightshade
Yellow Dock
Other health conditions supported by Mullein
Allergies (respiratory)Asthma
Bronchitis
Chronic Obstructive Pulmonary Disorder
Congestion (bronchial)
Congestion (lungs)
Cough (dry)
Cough (general)
Cough (spastic)
Ear Infection or Earache
Emphysema
Inflammation
Laryngitis
Pertussis
Pleurisy
Pneumonia
Sinus Infection
Skin (infections)
Sore Throat
Tuberculosis
Wheezing
Wounds and Sores
Products containing Mullein
Nature's Sunshine Seasonal Allergy (Formerly ALJ)
Nature's Sunshine ALJ®
Nature's Sunshine Bronchial Formula (Ayurvedic)
Nature's Sunshine Bone/Skin Poultice
Nature's Sunshine CC-A With Yerba Santa Combination Extract
Nature's Sunshine Four
Nature's Sunshine Herbal Pumpkin
Nature's Sunshine I-X
Nature's Sunshine Lymphomax
Nature's Sunshine Mullein
Nature's Sunshine Para-Cleanse
Nature's Sunshine Pro-Pancreas Formula
Nature's Sunshine Respiratory System (Best by 2/28/2026)