Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the body system: Lungs
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Eicosapentaenoic acid (EPA) is an omega-3 fatty acid primarily found in fish oil. Its potential role in supporting the lungs is supported by a moderate body of scientific evidence. EPA has well-documented anti-inflammatory properties, which are relevant because many chronic lung diseases—such as asthma and chronic obstructive pulmonary disease (COPD)—involve inflammation of the airways. Several studies have explored EPA’s impact on lung function and respiratory health. For example, research published in American Journal of Respiratory and Critical Care Medicine (2000) and other journals has shown that omega-3 supplementation can reduce the production of pro-inflammatory eicosanoids and cytokines, which may benefit individuals with inflammatory lung conditions.
However, while observational and interventional studies suggest potential benefits, results are mixed and often limited by small sample sizes or short study durations. Meta-analyses indicate some improvement in certain clinical symptoms or markers of inflammation, but these findings are not always consistent. EPA is not universally accepted as a standard therapy for lung conditions, but it is sometimes used as an adjunct to conventional treatments, especially in populations with diets low in omega-3 fatty acids.
In summary, there is scientific rationale and some supporting evidence for the use of EPA in supporting lung health, especially regarding its anti-inflammatory effects, but the level of evidence is moderate rather than strong.
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Other body systems supported by EPA (eicosapentaenoic acid)
ArteriesBlood
Brain
Circulatory System
Eyes
Heart
Immune System
Intestinal System
Joints
Liver
Lungs
Prostaglandins
Reproductive System
Respiratory System
Skin