Evidence supporting the use of: Garlic bulb
For the body system: Hepatic System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Garlic bulb (Allium sativum) has a long history of use in traditional medicine, including for liver (hepatic) health. Modern scientific research has begun to investigate these traditional claims. Several preclinical studies (in vitro and animal models) have shown that garlic and its organosulfur compounds (such as allicin and S-allylcysteine) exhibit hepatoprotective effects. These studies suggest garlic may reduce liver enzymes, protect against liver fibrosis, and mitigate liver damage caused by toxins and oxidative stress. The proposed mechanisms include antioxidant activity, anti-inflammatory effects, and modulation of liver enzyme activity. There is also some evidence that garlic can reduce fat accumulation in the liver, which is relevant to non-alcoholic fatty liver disease (NAFLD).

However, evidence from well-conducted human clinical trials remains limited. Some small studies have shown improvements in liver enzyme levels and lipid profiles among patients with NAFLD or elevated liver enzymes, but the results are inconsistent and often limited by sample size and study quality. No major clinical guidelines currently endorse garlic for hepatic support, but the available scientific evidence—especially from animal studies—provides a plausible basis for its use. More rigorous human research is needed to fully confirm its efficacy and safety for liver health.

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