Evidence supporting the use of: Licorice root
For the health condition: Fatty Liver Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Licorice root (Glycyrrhiza glabra) has a long history of use in traditional medicine for liver-related ailments, and recent scientific research has begun to explore its potential benefits for fatty liver disease (hepatic steatosis). Several animal studies and a limited number of small human clinical trials suggest that licorice root extracts, particularly those standardized for glycyrrhizin, may have hepatoprotective effects. These effects are thought to be related to anti-inflammatory, antioxidant, and anti-fibrotic properties. Glycyrrhizin may reduce liver enzyme levels and decrease markers of inflammation in patients with non-alcoholic fatty liver disease (NAFLD).
However, the overall quality of evidence is modest. Most clinical studies are small, short-term, or lack rigorous controls, making it difficult to draw definitive conclusions. The mechanisms proposed include the modulation of inflammatory cytokines, reduction in oxidative stress, and improvement in lipid metabolism. While promising, these findings are not yet robust enough to warrant licorice root as a standard treatment for fatty liver disease. Furthermore, excessive use of licorice can lead to adverse effects such as hypertension and hypokalemia due to its mineralocorticoid activity.
In summary, while there is emerging scientific evidence that supports the potential benefit of licorice root for fatty liver disease, the strength of the evidence is currently limited. More large-scale, high-quality clinical trials are needed to confirm its efficacy and safety in this context.
Other ingredients used for Fatty Liver Disease
akkermansia muciniphilaalgal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
arjun tree
artichoke
astaxanthin
banaba
barberry
barley
beet
berberine
bifidobacterium bifidum
bifidobacterium longum
black garlic
sesame
branched-chain amino acids
butyrate triglyceride
canola oil
catechins
caterpillar mushroom
cauliflower
chia seed
chicory
chlorella
chokeberry
choline
conjugated linoleic acid (CLA)
turmeric
curcumin
cyclodextrin
dandelion
diallyl disulfide (DADS)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fenugreek
fiber blend (proprietary)
fish oil
fish protein
flavonols
flaxseed
ginger
grape
hesperetin
kelp
l-carnitine
l-glutathione
l-methionine
l-taurine
lecithin
licorice root
liquid liver fractions
marine lipid
medium chain triglycerides (MCT)
milk thistle
naringin
niacin (vitamin B3)
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-9 fatty acids
palmitoleic acid
perilla
phenolic acids
phosphatidylcholine
phospholipids
prebiotic blend (proprietary)
butyric acid
psyllium
reishi mushroom
resveratrol
silymarin
spirulina
tocotrienols
trans-pterostilbene
tributyrin
trimethylglycine (TMG)
triphala
Urolithin A
vitamin C
vitamin E
seaweed
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
enicostemma littorale
punarnava
picrorhiza kurroa
lingzhi
morus
ferulic acid
ganoderma
polyphenols
anemarrhena asphodeloides
coix
nopal
algae
AMP-activated protein kinase (AMPK)
ashitaba
4-hydroxyisoleucine
7,14-Hydroxy-Docosapentaenoic Acid
Arjuna
Apigenin
Aronia melanocarpa
Antrodia camphorata
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Algal protein
Alisma
Arabinoxylan
Argan nut oil
Anemarrhena
alpha Methyl Tetradecylthioacetic Acid
Apocynin
Arjunolic acid
Borotutu
Brutieridin
Brown Algae
Brassica
Berberis (unspecified)
Baicalein
Blakeslea trispora
Betanin
Bifidobacteria
bile acid
Baicalin
Carqueja
Chebulic acid
Camelina Oil
Coriander
chlorogenic acid
Cynarin
Cruciferous
Chitin-Glucan Complex
Caulerpa okamurae
Copalchi
Curcuma
Corilagin
Crocetin
Cynaropicrin
corosolic acid
Carnosic acid
Diallyl sulfide
Danshen
Dihydromyricetin
DL-Methionine
Decursin
D-Pinitol
Diosgenin
Dithiolthiones
Eicosapentaenoic Acid
Rhubarb
walnut
Zucchini
Other health conditions supported by licorice root
Abdominal PainAbrasions
Abscesses
Acid Indigestion
Acne
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Addison's Disease
Adenitis
Adrenal Fatigue
Afterbirth Pain
Age Spots
Allergies (respiratory)
Amenorrhea
Anal Fistula or Fissure
Anemia
Appetite (deficient)
Asthma
Autoimmune Disorders
Bronchitis
Canker Sores
Chemotherapy (reducing side effects)
Chicken Pox
Cholera
Chronic Obstructive Pulmonary Disorder
Cirrhosis of the Liver
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colic (adults)
Colic (children)
Colitis
Colon (atonic)
Colon (spastic)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (lymphatic)
Congestion (sinus)
Constipation (adults)
Contagious Diseases
Convalescence
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cramps (menstrual)
Crohn's Disease
Croup
Cushing's Disease
Cytomealovirus
Dyspepsia
Eczema
Emphysema
Endometriosis
Enteritis
Epstein Barr Virus
Estrogen (low)
Fatty Liver Disease
Fever
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Gas and Bloating
Gastritis
Gingivitis
Glands (swollen lymph)
Goiter
Gonorrhea
Gout
Grave's Disease
Hair (loss or thinning)
Hair Care (general)
Halitosis
Hangover
Headache (general)
Headache (sinus)
Headache (tension)
Heart (weakness)
Hemorrhoids
Hepatitis
Hernias
Herpes
Hiatal Hernia
Hiccups
Hot Flashes
Hypotension
Hypothyroid
Impetigo
Indigestion
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Itching
Itching Ears
Jaundice (adults)
Jock Itch
Kidney Infection
Laryngitis
Leaky Gut Syndrome
Leprosy
Lesions
Leucorrhea
Liver Detoxification
Lungs (fluid in)
Lyme Disease
Lymph Nodes or Glands (swollen)
Malaria
Mastitis
Measles
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Metabolic Syndrome
Mononucleosis
Mood Swings
Morning Sickness
Mumps
Nausea and Vomiting
Nephritis
Nervous Exhaustion
Nervousness
Night Sweating
Nocturnal Emission
Oral Surgery
Ovarian Pain
Overacidity
Pertussis
Pleurisy
PMS (general)
Pneumonia
Poison Ivy or Oak
Rashes and Hives
Rosacea
Sore Throat
Ulcers
Products containing licorice root
Nature's Sunshine Adrenal Support
Nature's Sunshine Anti-Gas (Chinese)
Nature's Sunshine Anti-Gas TCM
Nature's Sunshine Bronchial Formula (Ayurvedic)
Nature's Sunshine Breathe Activator TCM (formerly Breathe E-Z)
Nature's Sunshine C-X
Nature's Sunshine Combination CBG Extract
Nature's Sunshine Chinese TCM Positive Pack
Nature's Sunshine Chinese TCM Negative Pack
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Energ-V Capsules
Nature's Sunshine Female Comfort
Nature's Sunshine Gastro Health
Nature's Sunshine Glandular System
Nature's Sunshine Hepatic System
Nature's Sunshine HY-C
Nature's Sunshine HY-C TCM
Nature's Sunshine IF-C
Nature's Sunshine IF-C TCM
Nature's Sunshine Immune System
Nature's Sunshine Kidney Activator TCM
Nature's Sunshine Kidney Activator (Chinese)
Nature's Sunshine LB Extract
Nature's Sunshine Lower Bowel Stimulator (Formerly LBS II)
Nature's Sunshine LBS II
Nature's Sunshine Licorice Root
Nature's Sunshine Licorice Root Extract
Nature's Sunshine Liver Balance (Chinese)
Nature's Sunshine Liver Balance TCM
Nature's Sunshine Lung Support (Chinese)
Nature's Sunshine Lung Support TCM
Nature's Sunshine Magnesium
Nature's Sunshine Master Gland Formula®
Nature's Sunshine Mineral-Chi Tonic (Chinese)
Nature's Sunshine Mood Elevator (Chinese)
Nature's Sunshine Mood Elevator TCM
Nature's Sunshine Nature's Chi TCM
Nature's Sunshine Natural Changes
Nature's Sunshine Pro-Pancreas Formula
Nature's Sunshine PS II
Nature's Sunshine Psyllium Hulls Combo
Nature's Sunshine Red Beet Root Formula
Nature's Sunshine Respiratory System (30 Day Program)
Nature's Sunshine SF
Nature's Sunshine Skeletal Strength
Nature's Sunshine Spleen Activator (Chinese)
Nature's Sunshine Spleen Activator TCM
Nature's Sunshine Stomach Comfort (Chewable)
Nature's Sunshine Stress Relief
Nature's Sunshine Stress Relief TCM
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Tiao He Cleanse
Nature's Sunshine Trigger Immune (Chinese)
Nature's Sunshine Trigger Immune TCM
Nature's Sunshine Ultimate GreenZone
Nature's Sunshine Ultimate Greenzone
Nature's Sunshine VS-C
Nature's Sunshine VS-C
Nature's Sunshine VS-C® TCM
Nature's Sunshine Women's X-Action
