Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Licorice root (Glycyrrhiza glabra) has a long history of use in traditional medicine systems, particularly in Traditional Chinese Medicine (TCM) and Ayurveda, for supporting liver health and managing liver disorders such as cirrhosis. In TCM, licorice root is considered to harmonize the ingredients in herbal formulas and is believed to possess hepatoprotective (liver-protecting) properties. Its inclusion in traditional remedies for "liver heat" or hepatic inflammation is well-documented. The primary active compound, glycyrrhizin, is thought to have anti-inflammatory and immunomodulatory effects, which could theoretically benefit liver function or slow the progression of liver damage.

However, scientific evidence supporting the use of licorice root specifically for cirrhosis of the liver is limited and largely based on animal studies or small-scale human trials. Some research suggests glycyrrhizin may help reduce liver enzyme levels and inflammation in certain liver conditions, but robust clinical trials in cirrhosis patients are lacking. Systematic reviews generally conclude that while licorice and glycyrrhizin show promise for various liver diseases, evidence for their effectiveness in cirrhosis is insufficient. Additionally, long-term or high-dose use of licorice root can lead to serious side effects such as hypertension and electrolyte imbalances.

In summary, licorice root's use for cirrhosis is primarily based on traditional practices rather than strong scientific validation.

More about licorice root
More about Cirrhosis of the Liver

Other ingredients used for Cirrhosis of the Liver

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