Evidence supporting the use of: Orange
For the health condition: Circulation (poor)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Oranges, particularly their peels and extracts, have traditionally been used in herbal and folk medicine to support circulation and cardiovascular health. The rationale stems from the presence of bioactive compounds such as flavonoids (notably hesperidin and naringenin), which are believed to strengthen blood vessel walls and improve microcirculation. In traditional Chinese medicine and Mediterranean herbalism, orange peel is sometimes used in formulations aimed at invigorating the blood and addressing symptoms such as cold extremities or varicose veins.
However, while there is a long-standing tradition of using oranges and their derivatives for circulatory support, the scientific evidence directly linking orange or its components to significant improvements in circulation is limited. Some small clinical studies and in vitro research have shown that citrus flavonoids can have beneficial effects on endothelial function, reduce inflammation, and improve capillary resistance, which may theoretically support circulation. Hesperidin, in particular, is sometimes used in supplements for chronic venous insufficiency, although these products often use purified or concentrated forms rather than whole orange fruit or juice.
Overall, while traditional use is well documented and there are promising early scientific findings concerning specific compounds found in oranges, robust clinical evidence confirming their effectiveness for treating poor circulation remains limited. Thus, oranges are primarily supported by tradition in this context, with some preliminary scientific support but not at the level of strong clinical validation.
Other ingredients used for Circulation (poor)
acetyl l-carnitineajoene
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
arjun tree
ashwagandha
asparagus
astaxanthin
astragalus
beet
bergamot
berry flavor
bilberry
black cumin
black currant
black garlic
black pepper
sesame
black tea
blueberry
bromelain
bupleurum falcatum
burdock
butcher's broom
caffeine
capsaicinoids
cat's claw
caterpillar mushroom
celery
chen pi
cherry
Chinese salvia root
chokeberry
cinnamon
citrus bioflavonoids
citrus sinensis (proprietary)
clove
coenzyme Q10 (CoQ10)
coleus forskohlii
cordyceps
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
dong quai root
eleuthero
EPA (eicosapentaenoic acid)
fish oil
fish protein
flavonols
flaxseed
fruit and vegetable blend (proprietary)
garlic bulb
ginger
ginkgo biloba
ginseng
gooseberry
gotu kola
grape
onion
green tea
greens blend (proprietary)
hawthorn
hesperetin
hesperidin
hibiscus
horse chestnut
horseradish
Indian tinospora
iron
knotweed
kudzu
l-arginine
l-carnitine
l-citrulline
lovage
mackerel
magnesium
marine lipid
moringa
mustard seed
naringin
nattokinase
nettle
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
orange
oyster mushroom
pine bark
policosanol
pomegranate
quercetin
redcurrant
reishi mushroom
resveratrol
rhizome
rose hips
rosemary
rutin
safflower oil
sardines
shiitake mushroom
black ginger
spinach
tocotrienols
triphala
ubiquinol
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
vitamin B
vitamin E
seaweed
water
watercress
watermelon
mulberry
sarsaparilla
suma
jiaogulan
tangerine
gastrodia
cardamom
atractylodes
capsicum
Indian bael
inula racemosa
punarnava
commiphora
smilax
blackboard tree
caesalpinia crista
peony
lingzhi
lingusticum wallichii
prickly ash
siler root
cistanche
dioscorea
dodder
ganoderma
morinda
zanthoxylum
birch
polyphenols
purslane
yerba mate
biota seed
goji berry
herbal blend (proprietary)
Sichuan pepper
yohimbe
cocoa
AMP-activated protein kinase (AMPK)
enzymes blend (proprietary)
cayenne pepper
ashitaba
2-(nitrooxy)ethyl 2-amino-3-methylbutanoate
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Aralia
Arjuna
Arginine Alpha Ketoglutarate
Antler
Autumn elaeagnus
Arginine Creatine
Arginine nitrate
Angelica
Aronia melanocarpa
Allicin
Arginine aspartate
Achyranthes
Auricularia
Adrenergic amines
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Asteracea
Arjunic Acid
Alliin
anthocyanosides
Allium tuberosum
Arginine silicate
Atractylone
Bishop's Weed
Butea monosperma
Black galingale
berry
Bur-Reed
Bioflavonoids
Bee products
Buddha's Hand
Buckwheat
Bassia scoparia
Boerhavia diffusa
Borneol
Coumarin
Centella triterpenes
Chinese Silkvine
Cinnamomum
Chinese Mountain Ant
Carqueja
Calycosin
Capsinoids
Codonopsis
Capillary Artemisia
Cyanidin
Curcuminoid
Citrus
Capsaicin
Catecholamine
Cowherb
Curcumen
Centella asiatica
Coca
Chocolate
Curcuma
Chestnut
Cinnamaldehyde
Costus
Carthamus
cola nut
Currant
Diallyl sulfide
Diosmin
Dismutase
Danshen
Dong Quai
Date
Diosmetin
Dodeca-2E, 4E, 8Z, 10Z/Etetraenoic Acid Isobutylamide
Elk antler
Eicosapentaenoic Acid
Ethylenediaminetetraacetic acid (EDTA)
Echium
Garlic
Mustard
Mistletoe
Pistachio
Sumac
Sweet Orange alcohol
yohimbine
Zucchini
Other health conditions supported by orange
AnemiaAppetite (deficient)
Arthritis
Asthma
Bronchitis
Bruises (healing)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Colds (general)
Colds (prevention)
Constipation (adults)
Constipation (children)
Cough (general)
Cough (spastic)
Dehydration
Digestion (poor)
Fatigue
Fever
Gingivitis
Hair Care (general)
Hangover
Hypertension
Indigestion
Inflammation
Insomnia
Kidney Stones
Liver Detoxification
Nausea and Vomiting
Night Blindness
Pain (general remedies for)
Products containing orange
Nature's Sunshine Calcium-Magnesium (SynerPro)
Nature's Sunshine Chinese TCM Positive Pack
Nature's Sunshine Glandular System
Nature's Sunshine Grapine With Protectors (SynerPro)
Nature's Sunshine Hepatic System
Nature's Sunshine HistaBlock
Nature's Sunshine Liver Balance TCM
Nature's Sunshine LOCLO
Nature's Sunshine MetaboMax Free
Nature's Sunshine MetaboMax Plus
Nature's Sunshine Mood Elevator (Chinese)
Nature's Sunshine Mood Elevator TCM
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine Nervous System (30 Day Program)
Nature's Sunshine Power Greens
Nature's Sunshine Power Greens To-Go
Nature's Sunshine Power Meal
Nature's Sunshine Power Meal
Nature's Sunshine Seasonal Defense
Nature's Sunshine Sunshine Heroes Whole Food Papayazyme
Nature's Sunshine Sunshine Heroes Probiotic Power
Nature's Sunshine Sinus Support EF
Nature's Sunshine SnorEase
Nature's Sunshine Super Trio
Nature's Sunshine Tiao He Cleanse
Nature's Sunshine Citrus Bioflavonoids (Vitamin C)