Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid) has some scientific basis for its use in the management of canker sores (aphthous ulcers), though the evidence is limited and not robust. Canker sores are small, painful ulcers that occur inside the mouth, and their exact cause is not fully understood, but they are sometimes associated with minor trauma, stress, immune dysfunction, or nutritional deficiencies—including vitamin C deficiency.

Vitamin C plays a critical role in collagen synthesis, wound healing, and immune system support. Historically, deficiency in vitamin C (scurvy) often manifests with gum disease and oral ulcerations, which supports the rationale that adequate vitamin C is necessary for oral mucosal health. Some small clinical studies and case reports have found that vitamin C supplementation, particularly in individuals with a deficiency, may reduce the frequency or severity of canker sores or speed their healing. For example, a few trials have reported reduced healing time and pain intensity when vitamin C was administered, either orally or as a topical preparation.

However, the majority of available studies are small, lack rigorous controls, or are of low quality. Systematic reviews and meta-analyses have concluded that, while vitamin C supplementation may be helpful in cases of deficiency, there is insufficient strong evidence to recommend routine use of vitamin C for canker sores in the general population. Most clinical guidelines do not list vitamin C as a first-line treatment, but supplementation may be considered in people who are at risk of deficiency.

More about vitamin C
More about Canker Sores

Other ingredients used for Canker Sores

Other health conditions supported by vitamin C

Products containing vitamin C

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Nature's Sunshine Nervous System (30 Day Program)
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