Evidence supporting the use of: Licorice root
For the body system: Spleen
Synopsis
Source of validity: Traditional
Rating (out of 5): 3
Licorice root (Glycyrrhiza glabra) has a longstanding role in Traditional Chinese Medicine (TCM), where it is used to "tonify" the Spleen, harmonize the actions of other herbs, and support digestive health. In TCM, the Spleen refers not only to the anatomical organ but also to a broader system responsible for digestion, nutrient absorption, and energy (Qi) production. Licorice root is classified as a sweet, neutral herb that enters the Spleen and other channels. Herbal formulas often include licorice root to strengthen the Spleen’s function, reduce fatigue, and improve appetite.
From a scientific perspective, licorice root contains compounds like glycyrrhizin, which have demonstrated anti-inflammatory and gastroprotective properties. However, Western medicine does not recognize the TCM "Spleen" as a physiological system, and studies have not directly investigated licorice root’s effects on the anatomical spleen or its Western-defined functions. Most clinical research focuses on licorice’s effects on the digestive tract, liver, and immune modulation, rather than specifically supporting the spleen. Therefore, the use of licorice root to support the Spleen is justified by strong traditional use and theory, with only indirect or tangential scientific support related to digestion and immunity.
In summary, licorice root’s use for the Spleen body system is primarily rooted in traditional herbal practice, with moderate evidence from clinical and pharmacological research supporting its broader digestive and immune effects.
Other ingredients that support Spleen
green chirettaapple
apricot
artichoke
astragalus
myrobalan
Beta-Glucan
black garlic
blackberry
bovine liver
bovine spleen
broccoli
rice
bupleurum falcatum
catechins
catjang cowpea
cauliflower
chaga mushroom
chamomile
chen pi
collard
Coptis chinensis
turmeric
curcumin
dandelion
diallyl disulfide (DADS)
dyer’s woad root
eleuthero
fruit and vegetable blend (proprietary)
fruit blend (proprietary)
fu ling
gardenia
garlic bulb
ginger
ginseng
glehnia root
goldenseal
gooseberry
grape
onion
green tea
Indian tinospora
iron
knotweed
jujube
kale
kelp
lemon
lentinula edodes mycelia
licorice root
liquid liver fractions
luteolin
maitake mushroom
mango
mangosteen
moringa
oleanolic acid
ophiopogon root
orange
parsley
perilla
pollen
pomegranate
pumpkin
quinoa
raspberry
rehmannia glutinosa
reishi mushroom
rhizome
schizonepeta
shiitake mushroom
spinach
strawberry
triphala
almond fruit
turkey tail mushroom
vegetable and fruit blend (proprietary)
vegetable blend (proprietary)
vitamin B
seaweed
water
mulberry
red clover
jiaogulan
chickweed
oryza
tangerine
hyssop
atractylodes
mugwort
inula racemosa
pistacia integerrima gall
punarnava
tinospora cordifolia
fumaria parviflora
picrorhiza kurroa
swertia
bee pollen
peony
lingzhi
lingusticum wallichii
yarrow
morus
root tuber
silk tree
flowering quince
dioscorea
ganoderma
hyacinth bean
lotus seed
morinda
oriental arborvitae
tartarian aster
trichosanthes
zanthoxylum
trace minerals
coix
wheat germ
noni
millet seed
algae
ashitaba
Aralia
Alpha Glucans
Agastache
Anamarrhena
Ankaflavin
Angelica
Antrodia camphorata
Auricularia
Abrus
Amomum
Albizia
Andrographolide
Asam gelugor
Astragaloside
Armillaria mellea
Alsonia scholaris
Ampelopsis
Agrimonia pilosa
Asteracea
Alkylglycerols
Adenophora
Artemisia Anomala
Anemarrhena
Allium tuberosum
Alstonia macrophylla
Atractylone
Animal protein
Black Seed
Baikal Skullcap
Baliospermum
Baphicacanthus cusia
Bidens pilosa
Broussonetia
bergenin
Breadnut
Brassica
Belleric myrobalan
Beef liver
Berberis (unspecified)
Bok Choy
Baicalein
Bovine Protein
Bael
Basidiomycota
berry
Bee products
Bombax
Borassus Palm
Bupleurum
Baicalin
Cumin
Cinnamomum
Carqueja
Clerodendrum trichotomum
Cucurbita
Calycosin
Coriolus mushroom
Combretum quadrangulare
Codonopsis
Capillary Artemisia
Curcuminoid
Citrus
Cantaloupe
Chinese Raisintree
Cowherb
Cruciferous
Curcumen
Capers
Chard
Chicken
Curcuma
Carob
Chirata
Cornus
Chaenomeles lagenaria
Chinese Thoroughwax
Cephalotaxus sinensis
Ceanothus integerrimus
Chebulinic acid
Costus
Cynanchum
Danshen
Dendrobium
Dolichos
Deoxyandrographolides
Dulse
Erodium cicutarium
eggplant
Egg
Emblicanin
Elkweed
Emodin
Enokitake
Goldthread
Garlic
Lotus
Orchid
Sumac
walnut
Other body systems supported by licorice root
Adrenal CortexAdrenal Glands
Blood
Cortisol
Digestive System
Estrogen
Eustachian Tubes
Gastrointestinal Tract
Glandular System
Gums
Immune System
Intestinal System
Large Intestines (Colon)
Liver
Lungs
Lymphatics
Mucus Membranes
Ovaries
Pituitary
Reproductive System
Respiratory System
Sinuses
Skin
Solar Plexus
Specific Hormones
Spleen
Stomach
Sympathetic Nervous System
Teeth
Thymus
Thyroid Gland
Tonsils
Uterus
Vagina
Vocal Cords
Products containing licorice root
Nature's Sunshine Adrenal Support
Nature's Sunshine Anti-Gas (Chinese)
Nature's Sunshine Anti-Gas TCM
Nature's Sunshine Bronchial Formula (Ayurvedic)
Nature's Sunshine Breathe Activator TCM (formerly Breathe E-Z)
Nature's Sunshine C-X
Nature's Sunshine Combination CBG Extract
Nature's Sunshine Chinese TCM Positive Pack
Nature's Sunshine Chinese TCM Negative Pack
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Energ-V Capsules
Nature's Sunshine Female Comfort
Nature's Sunshine Gastro Health
Nature's Sunshine Glandular System
Nature's Sunshine Hepatic System
Nature's Sunshine HY-C
Nature's Sunshine HY-C TCM
Nature's Sunshine IF-C
Nature's Sunshine IF-C TCM
Nature's Sunshine Immune System
Nature's Sunshine Kidney Activator TCM
Nature's Sunshine Kidney Activator (Chinese)
Nature's Sunshine LB Extract
Nature's Sunshine Lower Bowel Stimulator (Formerly LBS II)
Nature's Sunshine LBS II
Nature's Sunshine Licorice Root
Nature's Sunshine Licorice Root Extract
Nature's Sunshine Liver Balance (Chinese)
Nature's Sunshine Liver Balance TCM
Nature's Sunshine Lung Support (Chinese)
Nature's Sunshine Lung Support TCM
Nature's Sunshine Magnesium
Nature's Sunshine Master Gland Formula®
Nature's Sunshine Mineral-Chi Tonic (Chinese)
Nature's Sunshine Mood Elevator (Chinese)
Nature's Sunshine Mood Elevator TCM
Nature's Sunshine Nature's Chi TCM
Nature's Sunshine Natural Changes
Nature's Sunshine Pro-Pancreas Formula
Nature's Sunshine PS II
Nature's Sunshine Psyllium Hulls Combo
Nature's Sunshine Red Beet Root Formula
Nature's Sunshine Respiratory System (30 Day Program)
Nature's Sunshine SF
Nature's Sunshine Skeletal Strength
Nature's Sunshine Spleen Activator (Chinese)
Nature's Sunshine Spleen Activator TCM
Nature's Sunshine Stomach Comfort (Chewable)
Nature's Sunshine Stress Relief
Nature's Sunshine Stress Relief TCM
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Tiao He Cleanse
Nature's Sunshine Trigger Immune (Chinese)
Nature's Sunshine Trigger Immune TCM
Nature's Sunshine Ultimate GreenZone
Nature's Sunshine Ultimate Greenzone
Nature's Sunshine VS-C
Nature's Sunshine VS-C
Nature's Sunshine VS-C® TCM
Nature's Sunshine Women's X-Action