Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Fish oil, rich in omega-3 fatty acids such as EPA and DHA, has been investigated for its potential role in migraine prevention and management. Several small-scale clinical trials and observational studies suggest that omega-3 supplementation may reduce the frequency, duration, or severity of migraine attacks. The proposed mechanism involves the anti-inflammatory properties of omega-3 fatty acids, which may help modulate the production of pro-inflammatory eicosanoids and cytokines implicated in migraine pathogenesis. Additionally, omega-3s may affect platelet aggregation and vascular function, both of which are relevant to the complex pathophysiology of migraines.

However, the evidence remains preliminary and somewhat inconsistent. Some randomized controlled trials have demonstrated modest benefits, while others have found no significant effect compared to placebo. Meta-analyses and systematic reviews generally conclude that, although fish oil is safe and well-tolerated, the quality of evidence supporting its use for migraine is low to moderate, and larger, well-designed studies are needed to confirm efficacy. Thus, while there is a scientific rationale and some clinical support, fish oil is not a universally accepted or primary therapy for migraines. Its use is often considered as an adjunct to standard treatments rather than a stand-alone intervention.

More about fish oil
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Other ingredients used for Migraine

Other health conditions supported by fish oil

Products containing fish oil

Nature's Sunshine Circulatory System
Nature's Sunshine DHA
Nature's Sunshine Krill Oil (With Vitamin K2)
Nature's Sunshine Super Omega 3 EPA
Nature's Sunshine Super Omega 3 EPA
Nature's Sunshine Super Trio