Evidence supporting the use of: Chamomile
For the health condition: Chemotherapy (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Chamomile (Matricaria chamomilla) has been traditionally used for its calming, anti-inflammatory, and soothing properties, but recent scientific research has begun to explore its role in supporting cancer patients undergoing chemotherapy, particularly for managing side effects such as oral mucositis and gastrointestinal discomfort.

Several small clinical studies have evaluated the topical use of chamomile, particularly as a mouth rinse, in reducing the severity and incidence of oral mucositis—a common and painful complication of chemotherapy and radiotherapy. A 2015 randomized controlled trial published in the journal Supportive Care in Cancer found that a chamomile mouthwash significantly reduced the severity of oral mucositis in patients undergoing chemotherapy compared to placebo. Other studies have reported similar benefits, though most were limited by small sample sizes and methodological limitations.

Chamomile is also sometimes used to alleviate chemotherapy-induced nausea or gastrointestinal irritation, owing to its mild antispasmodic effects. However, evidence in this area is less robust, with few high-quality studies available.

Overall, while there is emerging scientific support—particularly for topical use of chamomile in oral mucositis—the evidence base remains limited (rated 2/5). Chamomile is generally considered safe when used appropriately, but cancer patients should consult their healthcare providers before using herbal remedies, as interactions with chemotherapy drugs are possible.

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Other ingredients used for Chemotherapy (reducing side effects)

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Acemannan
AHCC
Alkylglycerols
Aloe vera
Alpha Glucans
Alpha lactalbumin
alpha-glycosyl isoquercitrin
alpha-ketoglutarate (AKG)
alpha-lipoic acid
amino acids
anthocyanins
Antrodia camphorata
astaxanthin
astragalus
Baikal Skullcap
BCAA
benzyl isothiocyanate
beta caryophyllene
Bifidobacteria
Bifidobacterium
Bifidobacterium adolescentis
Bifidobacterium animalis
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
black cumin
black currant
blueberry
Boswellic Acid
branched-chain amino acids
bromelain
C-phycocyanin
cannabidiol
cannabigerol
Cannabis sativa oil
caryophyllene
chamomile
chlorella
Clostridium butyricum
Codonopsis
coenzyme Q10 (CoQ10)
coix
colostrum
curcumin
Curcuminoid
cyclodextrin
d-alpha tocopherol
dithiolthiones
ergothioneine
fish oil
folinic acid
fucoidan
ginger
Glutamine
Glutathione
grape
green tea
Haematococcus pluvialis
hemp
hemp oil
herbal blend (proprietary)
hericium mushroom
HMB hydroxymethylbutyrate
Honokiol
hydroxymethylbutyrate
Hyphomycetes
L-alanyl-L-glutamine
L-carnosine
L-cysteine
L-glutamine
L-glutathione
L-glycine
L-taurine
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus lactis
Lactobacillus plantarum
Lactoferrin
lactoglobulin
Lentinan
Lentinula edodes mycelia
licorice root
lion's mane
luteolin
Marine lipid
Matcha
Melatonin
Mesima
Methylselenocysteine
Milk Protein
Milk thistle
Mistletoe
Mushroom
N-acetyl-cysteine (NAC)
Oldenlandia diffusa
Palmitoylethanolamide (PEA)
Peptides
Phenethyl isothiocyanate (PEITC)
phytocannabinoids
polysaccharides
pomegranate
probiotics
protein
pyridoxal-5-phosphate (P-5-P)
quercetin
reishi mushroom
resveratrol
Saccharomyces boulardii
Saccharomyces cerevisiae
selenium
Selenomethionine
shiitake mushroom
Silychristin
soy isoflavones
spirulina
streptococcus thermophilus
Sulforaphane
Thymidine
Thymoquinone
tributyrin
Turkey tail mushroom
turmeric
Typhonium flagelliforme
Verbascoside
vitamin B6
vitamin C
vitamin E
Whey protein
Zinc

Other health conditions supported by chamomile

Abdominal Pain
Abrasions
Abscesses
Abuse and Trauma
Acid Indigestion
Acne
Addictions (general remedies for)
Adrenal Fatigue
Afterbirth Pain
Age Spots
Allergies (respiratory)
Anal Fistula or Fissure
Antibiotics (side effects of)
Anxiety
Anxiety Disorders
Appetite (deficient)
Anger (excessive)
Bedwetting
Belching
Bites and Stings
Bleeding (external)
Blisters
Bloodshot Eyes
Boils
Bruises (healing)
Bulimia
Burns and Scalds
Cancer (natural therapy for)
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Chemotherapy (reducing side effects)
Colds (general)
Colds (prevention)
Colds (with fever)
Colic (adults)
Colic (children)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Constipation (adults)
Constipation (children)
Cuts
Depression
Dermatitis
Diarrhea
Digestion (poor)
Dysmenorrhea
Dyspepsia
Ear Infection or Earache
Eczema
Emotional Sensitivity
Enteritis
Epilepsy
Eye Infections
Eye Problems
Eyes (red or itching)
Fever
Fungal Infections
Gas and Bloating
Gastritis
Gingivitis
Halitosis
Headache (general)
Headache (sinus)
Headache (tension)
Hemorrhoids
Hiatal Hernia
Hiccups
Hysteria
Indigestion
Inflammatory Bowel Disorders
Insomnia
Irritability
Itching
Itching (rectal)
Itching Ears
Labor and Delivery
Laryngitis
Leaky Gut Syndrome
Lesions
Lupus
Measles
Morning Sickness
Nausea and Vomiting
Nose Bleeds
Perspiration (excessive)
PMS (general)
PMS Type A
PMS Type P
Poison Ivy or Oak
Post Partum Depression
Post Traumatic Stress Disorder
Pregnancy (herbs and supplements for)
Rashes and Hives
Restless Dreams
Rhinitis
Rhinitis, Allergic
Rosacea
Scratches and Abrasions
Seizures
Sleep (restless and disturbed)
Sore Throat
Strep Throat
Stress
Sunburn
Sweat Baths (herbs for)
Teething
Tension
Tickle in Throat
TMJ
Tonsillitis