Evidence supporting the use of: Magnesium
For the health condition: Autoimmune Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Magnesium is an essential mineral involved in numerous physiological processes, including immune system regulation. There is emerging scientific evidence suggesting that magnesium plays a role in modulating immune responses, which has led to interest in its potential to support individuals with autoimmune disorders. Research indicates that magnesium deficiency is associated with increased inflammation and dysregulation of immune function, both of which are relevant in the context of autoimmune diseases. Some observational studies have reported lower magnesium levels in patients with autoimmune conditions such as multiple sclerosis, rheumatoid arthritis, and lupus compared to healthy controls. Additionally, animal and in vitro studies suggest that magnesium can influence the activity of T cells and cytokine production, which are critical components of autoimmune pathology.

However, the direct evidence from randomized controlled trials (RCTs) in humans demonstrating that magnesium supplementation improves clinical outcomes in autoimmune disorders is limited. Most of the supporting data is indirect, focusing on the mineral's general anti-inflammatory properties and its necessity for overall immune health, rather than specific effects on autoimmune disease progression or symptoms. Current clinical guidelines do not recommend magnesium supplementation as a primary treatment for autoimmune disorders, though correcting a deficiency is considered good medical practice.

In summary, while the biological plausibility and indirect evidence are promising, robust human trials specifically targeting autoimmune conditions are lacking. Therefore, magnesium’s use is scientifically plausible but not yet strongly validated for treating autoimmune disorders.

More about magnesium
More about Autoimmune Disorders

Other health conditions supported by magnesium

Addictions (drugs)
Addictions (general remedies for)
Aging (prevention)
Alcoholism
Alkalosis
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Autoimmune Disorders
Backache
Bipolar Mood Disorder
Birth Control (countering side effects)
Body Building
Body Odor
Boils
Broken Bones
Bronchitis
Bulimia
Calcium Deficiency
Calcium Deposits
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiac Arrest
Cardiovascular Disease
Chest Pain
Colon (atonic)
Dysmenorrhea
Emotional Sensitivity
Endurance (lack of)
Energy (lack of)
Epilepsy
Exercise
Fatigue
Fibromyalgia Syndrome
Headache (cluster)
Headache (tension)
Hearing Loss
Heart (weakness)
Mental Illness
Migraine
Mood Swings
Muscle Tone (lack of)
Nerve Damage
Nervous Exhaustion
Nervousness
Neurosis
Numbness
Osteoporosis
Oxygen Deficiency
Pain (general remedies for)
Paralysis
Pets (supplements for)
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Pregnancy (herbs and supplements for)
Progesterone (low)
Psoriasis
Restless Leg Syndrome
Rhinitis
Seasonal Affective Disorder
Seizures
Senility
Shock
Skin (dry and/or flaky)
Skin Care (general)
Sleep (restless and disturbed)
Stress
Sugar Cravings
Surgery (healing from)
Surgery (preparation for)
Tachycardia
Tension
Testosterone (low)
Tetanus
Thinking (cloudy)
Tics
Tinnitus
TMJ
Tooth Decay
Toxemia
Triglycerides (high)
Twitching
Wasting
Wheezing
Worry
Wounds and Sores
Adrenal Fatigue
Abscesses
Allergies (respiratory)
Abdominal Pain
Acid Indigestion
Cholesterol (high)
Circulation (poor)
Constipation (adults)
Convulsions
Cramps (leg)
Cramps (menstrual)
Cramps and Spasms
Depression
Diabetes
Digestion (poor)
Dizziness
Gastritis
Headache (general)
Heart Fibrillation or Palpitations
Hypertension
Insomnia