Evidence supporting the use of: Magnesium
For the body system: Uterus

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Magnesium is scientifically validated for certain uses in supporting the uterus, particularly in obstetric and gynecological contexts. Its most established use is in the management of preeclampsia and eclampsia (severe complications of pregnancy characterized by high blood pressure and risk of seizures). Magnesium sulfate is the standard treatment to prevent and control eclamptic seizures, and this practice is widely endorsed by clinical guidelines and supported by multiple randomized controlled trials and systematic reviews.1 Beyond eclampsia, some evidence suggests magnesium may help reduce the frequency and severity of uterine muscle cramps (dysmenorrhea) and premenstrual syndrome (PMS) symptoms, although results are mixed and the studies are generally of moderate quality.2 Magnesium is believed to influence smooth muscle contractility by blocking calcium channels, which can help relax uterine muscles and reduce spasms. However, for the routine support of general uterine health in non-pregnant women, the evidence is less robust. Its use outside of the above indications is not broadly supported by high-quality research. Thus, while there is scientific validation for magnesium’s use in specific uterine-related conditions, especially in pregnancy complications, the overall strength of evidence for general uterine support is moderate.
1 Altman D, Carroli G, Duley L, et al. Do women with pre-eclampsia, and their babies, benefit from magnesium sulphate? The Magpie Trial: a randomised placebo-controlled trial. Lancet. 2002.
2 Proctor ML, Murphy PA. Herbal and dietary therapies for primary and secondary dysmenorrhoea. Cochrane Database Syst Rev. 2001.

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