Evidence supporting the use of: Magnesium
For the health condition: Twitching

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Magnesium is commonly used to support or treat muscle twitching, a condition also known as fasciculation. Scientifically, magnesium plays a crucial role in nerve transmission and muscle contraction. It acts as a natural calcium antagonist at neuromuscular junctions, helping to regulate the excitability of nerves and muscles. Magnesium deficiency can result in increased neuromuscular excitability, which may manifest as muscle cramps, spasms, or twitching.

Several observational and interventional studies have shown that low magnesium status is associated with muscle twitching and cramps, especially in populations at risk of deficiency, such as athletes, older adults, and pregnant women. Supplementation with magnesium has shown benefit in some trials, particularly for leg cramps in pregnancy and in certain cases of chronic muscle twitching due to deficiency. However, the evidence is variable and some randomized controlled trials have not shown significant effects in all populations, leading to a moderate evidence rating.

Despite these mixed results, the biological plausibility supported by clinical experience and the relatively low risk of side effects make magnesium supplementation a reasonable first-line approach when muscle twitching is suspected to be related to deficiency. Clinical guidelines often recommend magnesium assessment and supplementation in cases of unexplained neuromuscular symptoms, especially if dietary intake is low or there are other risk factors for deficiency.

More about magnesium
More about Twitching

Other ingredients used for Twitching

magnesium
vitamin B6

Other health conditions supported by magnesium

Addictions (drugs)
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Aging (prevention)
Alcoholism
Alkalosis
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
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Athletic and Exercise Aids
Attention Deficit Disorder
Autism
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Backache
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Birth Control (countering side effects)
Body Building
Body Odor
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Bronchitis
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Calcium Deficiency
Calcium Deposits
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
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Cardiovascular Disease
Chest Pain
Colon (atonic)
Dysmenorrhea
Emotional Sensitivity
Endurance (lack of)
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Epilepsy
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Fatigue
Fibromyalgia Syndrome
Headache (cluster)
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Hearing Loss
Heart (weakness)
Mental Illness
Migraine
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Muscle Tone (lack of)
Nerve Damage
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Nervousness
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Numbness
Osteoporosis
Oxygen Deficiency
Pain (general remedies for)
Paralysis
Pets (supplements for)
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Pregnancy (herbs and supplements for)
Progesterone (low)
Psoriasis
Restless Leg Syndrome
Rhinitis
Seasonal Affective Disorder
Seizures
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Skin (dry and/or flaky)
Skin Care (general)
Sleep (restless and disturbed)
Stress
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Surgery (healing from)
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Tachycardia
Tension
Testosterone (low)
Tetanus
Thinking (cloudy)
Tics
Tinnitus
TMJ
Tooth Decay
Toxemia
Triglycerides (high)
Twitching
Wasting
Wheezing
Worry
Wounds and Sores
Adrenal Fatigue
Abscesses
Allergies (respiratory)
Abdominal Pain
Acid Indigestion
Cholesterol (high)
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Cramps and Spasms
Depression
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