Evidence supporting the use of: Caprylic acid
For the health condition: Thrush

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Caprylic acid, a medium-chain fatty acid found in coconut oil and palm oil, has been used as a natural remedy for Candida infections, including oral thrush (caused by Candida albicans). The scientific rationale for its use lies in its demonstrated antifungal activity. In vitro studies have shown that caprylic acid can disrupt the cell membranes of Candida species, leading to cell death. For example, research published in Antimicrobial Agents and Chemotherapy (1980) and subsequent studies have confirmed its fungicidal properties against a variety of Candida strains. Additionally, some animal studies have suggested that caprylic acid supplementation may help reduce intestinal Candida colonization. However, human clinical evidence remains limited. Most available studies are either test-tube or animal-based, and there is a lack of large, well-controlled trials examining caprylic acid’s effectiveness specifically for oral thrush in humans. Some integrative and alternative medicine practitioners recommend caprylic acid supplements or topical preparations for thrush based on its antifungal potential and relatively low toxicity. In summary, while there is a scientific basis for its use and some preliminary supporting evidence, the clinical effectiveness of caprylic acid for treating thrush in humans is not well established, justifying a moderate evidence rating.

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