Evidence supporting the use of: Trace minerals
For the body system: Structural System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Trace minerals, including elements like zinc, copper, manganese, selenium, and boron, are scientifically recognized as essential for the maintenance and development of the structural system, which includes bones, cartilage, and connective tissues. Numerous studies have demonstrated that these minerals serve as cofactors for enzymatic reactions critical to bone matrix formation and remodeling. For example, zinc is necessary for collagen synthesis and bone mineralization, while copper is involved in the cross-linking of collagen and elastin, contributing to bone strength and integrity. Manganese plays a role in the formation of bone cartilage and the synthesis of proteoglycans, essential components of the bone matrix. Selenium acts as an antioxidant, protecting bone cells from oxidative stress. Deficiencies in these trace minerals have been associated with impaired bone growth, increased risk of fractures, and bone deformities. Clinical and epidemiological studies support the role of adequate trace mineral intake in maintaining bone density and reducing the risk of osteoporosis. However, while the scientific foundation is strong for the necessity of trace minerals in bone health, the benefit of supplementation beyond a balanced diet remains less clear for the general population, except in cases of deficiency or increased physiological need.

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