Evidence supporting the use of: Vitamin B12
For the health condition: Sore or Geographic Tongue

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin B12 is used to support or treat sore tongue (glossitis) and geographic tongue primarily based on scientific rationale, although the strength of evidence is moderate and mostly relates to deficiency states. Vitamin B12 deficiency can manifest with oral symptoms, including soreness, burning, ulceration, and changes in the appearance of the tongue (such as atrophic glossitis, characterized by a smooth, sore tongue). Clinical studies and case reports have shown that supplementation with vitamin B12 can resolve these symptoms in individuals who are deficient. For example, a 2009 study in Oral Diseases found that patients with burning mouth syndrome and low B12 levels improved after supplementation. However, for "geographic tongue" (benign migratory glossitis), evidence is far less clear. Most cases of geographic tongue are idiopathic and not directly linked to B12 deficiency, though a few small studies and case reports have noted improvement in some patients after B12 supplementation, particularly if a deficiency is present. There is insufficient evidence to recommend B12 for geographic tongue in the absence of a documented deficiency. Overall, vitamin B12 is scientifically justified for sore tongue when deficiency is present, but its general use for geographic tongue is not strongly supported by high-quality studies.

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Other ingredients used for Sore or Geographic Tongue

aloe vera
vitamin B12
vitamin B6
zinc