Nature's Sunshine

Methyl Combo

60 capsules
Stock #: 21689
In Stock

$28.95 (Before 25% discount)
No Sales Tax!

Note: Save 25% on this product (coupon added at checkout automatically)

In stock

Important information

  • No sales tax
  • No membership requirements
  • No automatic shipments
  • 90 day FREE returns

Expiration Date: 12/2024

Shipping (1 unit): $2.99

FREE shipping on all orders over $75!

Product Information


  • Contributes to the maintenance of normal neurological and psychological functions*
  • Contributes to a reduction in tiredness and fatigue
  • Supports the nervous and immune systems
  • Provides nutrients essential for prenatal development
  • Veggie Capsule
  • Supports general well-being
  • How it Works

    In its natural form, folic acid has to pass through four enzymatic conversions before becoming the biologically active form of methyl folate known as methyltetrahydrofolate. Similarly, vitamin B12 has to pass through three enzymatic conversions before becoming the active form methylcobalamin. A 2008 study by the World Health Organization concluded that, “…deficiencies of [Folate and Vitamin B12] may be a public health problem that could affect many millions of people throughout the world.” Methyl Combo bypasses these conversion processes and delivers the active forms of B12 and Folic Acid, methylcobalamin and methylfolate. When these two influential vitamins are in their bioavailable state, they pair up and contribute to the methionine synthesis cycle. This cycle takes the Methyl Combo vitamins and creates methionine, an essential amino acid. Methionine is required for the healthy function of cells, proteins, enzymes, neurotransmitters, metabolic function, etc.


    1,000 mcg per serving of vitamin B12 sourced from methylcobalamin, 800 mcg per serving of folate sourced from methyltetrahyrdrofolate calcium salt

    Recommended Use

    Take 1 vegcap twice daily, or as directed by your healthcare practitioner.

    Product Label

    Easy Returns

    The Caring Sunshine return policy is both easy and generous. We accept returns for any reason for 90 days from the order date and we cover the shipping costs both ways. Read our full policy here.

    New label and other changes

    In the fall of 2020, Nature's Sunshine switched to a new label and changed the names of a few products. However, no formulas have been changed. To learn more about the changes, click here.

Customer Reviews

Based on 5 reviews
Great service and product

Quick service and product!

Debbie Klugman
Wonderful Product

Methyl combo is a great source of B12 and I don’t feel as good when I’m not taking it.

Helen Cruitt
Great value

Timely arrival

Daniel Vogel
My vitamin orders.

Good prices and easy to order.


We are using Methyl Combo to improve our health and it is excellent. We are feeling very good.

Nature's Sunshine Methyl Combo
Methyl Combo

In stock