Evidence supporting the use of: Vitamin C
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin C (ascorbic acid) is scientifically validated to play a crucial role in supporting the skeletal system, particularly in bone health and maintenance. Its primary function in this context is as a cofactor for enzymes involved in collagen synthesis. Collagen is a major structural protein in bone tissue, providing a framework for mineralization and contributing to bone strength and flexibility. Deficiency of vitamin C impairs collagen formation, leading to weakened bone matrix and, in severe cases, the development of scurvy, which is characterized by bone pain, impaired wound healing, and increased risk of fractures.

Research in both animal models and humans has demonstrated that vitamin C deficiency leads to defective bone formation and decreased bone density. Observational studies suggest that adequate vitamin C intake is associated with higher bone mineral density and reduced fracture risk, especially in older adults. However, evidence from randomized controlled trials on vitamin C supplementation for improving bone health in individuals with adequate intake is limited and mixed. Thus, while the biological role of vitamin C in bone formation is well-established, its therapeutic use for bone health beyond deficiency states is less clear.

In summary, vitamin C’s importance for bone health is grounded in biochemical and clinical evidence, justifying its use primarily for prevention and correction of deficiency rather than as a standalone supplement to enhance bone strength in otherwise healthy individuals.

More about vitamin C
More about Skeletal System (Bones)

Products containing vitamin C

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Nature's Sunshine MultiVitamin & Mineral (SynerPro)
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Nature's Sunshine Nature's Harvest
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Nature's Sunshine Nutri-Calm
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Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Immune
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Nature's Sunshine Super Supplemental
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Nature's Sunshine Vitamin C (1000 mg, Time Release)
Nature's Sunshine Vitamin C (1000 mg, Time Release)
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