Evidence supporting the use of: Vitamin C
For the body system: Skeletal System (Bones)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Vitamin C (ascorbic acid) is scientifically validated to play a crucial role in supporting the skeletal system, particularly in bone health and maintenance. Its primary function in this context is as a cofactor for enzymes involved in collagen synthesis. Collagen is a major structural protein in bone tissue, providing a framework for mineralization and contributing to bone strength and flexibility. Deficiency of vitamin C impairs collagen formation, leading to weakened bone matrix and, in severe cases, the development of scurvy, which is characterized by bone pain, impaired wound healing, and increased risk of fractures.
Research in both animal models and humans has demonstrated that vitamin C deficiency leads to defective bone formation and decreased bone density. Observational studies suggest that adequate vitamin C intake is associated with higher bone mineral density and reduced fracture risk, especially in older adults. However, evidence from randomized controlled trials on vitamin C supplementation for improving bone health in individuals with adequate intake is limited and mixed. Thus, while the biological role of vitamin C in bone formation is well-established, its therapeutic use for bone health beyond deficiency states is less clear.
In summary, vitamin C’s importance for bone health is grounded in biochemical and clinical evidence, justifying its use primarily for prevention and correction of deficiency rather than as a standalone supplement to enhance bone strength in otherwise healthy individuals.
Other ingredients that support Skeletal System (Bones)
alfalfaalpha-ketoglutarate (AKG)
amino acids
sesame
boron
Indian frankincense
bovine
bovine gelatin
broccoli
calcium
cartilage
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
collard
devil's claw
fish protein
gelatin
genistein
genistin
green lipped mussel
horsetail
ipriflavone
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
milk
phosphorus
protein
prune
rehmannia glutinosa
sardines
silicon
spinach
strontium
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
water
boneset
solomon's seal
eucommia
trace minerals
herbal blend (proprietary)
algae
soy isoflavones
Arugula
Antler
Achyranthes
Algas calcareas
Animal protein
Boswellic Acid
Beef
Bone Marrow
Baicalein
Bovine Protein
Borate
Boswellia
Bone Protein
bovine cartilage / glycosaminoglycan
Buckwheat
Comfrey
Chinese Silkvine
Chinese Mountain Ant
Citrate malate
Cod Liver Oil
Chinese Pond Turtle
Chuchuhuasi
Cruciferous
Corallina officinalis
Dolomite
Daidzein
Deer Velvet
Drynaria
Dipsacus
Egg
Elk antler
Glycosaminoglycans
Isoflavones
Molasses
Milk Protein
Phosphate Salt
Soy Protein
Other body systems supported by vitamin C
Adrenal GlandsAdrenal Medulla
Arteries
Blood
Brain
Capillaries
Circulatory System
Dopamine
Eyes
Gastrointestinal Tract
Glandular System
Gums
Hair
Heart
Immune System
Immune System
Intestinal System
Joints
Liver
Lungs
Mucus Membranes
Muscles
Nails
Respiratory System
Sinuses
Skeletal System (Bones)
Skin
Spinal Disks
Structural System
Teeth
Testes
Thymus
Tonsils
Veins
Veins
Vocal Cords
Products containing vitamin C
Nature's Sunshine Love and Peas (Sugar Free)
Nature's Sunshine Adrenal Support
Nature's Sunshine Bowel Detox
Nature's Sunshine Children's Elderberry Immune
Nature's Sunshine Children's MultiVitamin & Mineral
Nature's Sunshine Cortisol Formula (Nature's Cortisol Formula)
Nature's Sunshine Defense Maintenance
Nature's Sunshine Detox Basics (Best used by 7/31/25)
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Glandular System
Nature's Sunshine Grapine With Protectors (SynerPro)
Nature's Sunshine Hepatic System
Nature's Sunshine Iron (Chelated)
Nature's Sunshine Love and Peas
Nature's Sunshine Marine Collagen
Nature's Sunshine Marine Glo Collagen
Nature's Sunshine Master Gland Formula®
Nature's Sunshine Mega-Chel
Nature's Sunshine Milk Thistle Combination
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine MultiVitamin & Mineral (Time Release)
Nature's Sunshine Natural Changes
Nature's Sunshine Nature's Prenatal
Nature's Sunshine Nature's Harvest
Nature's Sunshine Nervous System (30 Day Program)
Nature's Sunshine Nutri-Calm
Nature's Sunshine Nutri-Calm
Nature's Sunshine Perfect Eyes
Nature's Sunshine Power Beets Pouch
Nature's Sunshine Power Beets To-Go Packs
Nature's Sunshine Power Greens
Nature's Sunshine Power Greens To-Go
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Immune
Nature's Sunshine Solstic Revive
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Vari-Gone
Nature's Sunshine Vitamin C (1000 mg, Time Release)
Nature's Sunshine Vitamin C (1000 mg, Time Release)
Nature's Sunshine Vitamin C Ascorbates
Nature's Sunshine Chewable Vitamin C
Nature's Sunshine Citrus Bioflavonoids (Vitamin C)
Nature's Sunshine Zinc Lozenge