Evidence supporting the use of: Bromelain
For the health condition: Rhinitis, Allergic

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bromelain, an enzyme extract derived from pineapples, has been investigated for its potential benefits in treating allergic rhinitis due to its anti-inflammatory and mucolytic properties. Several clinical studies and reviews support its use as an adjunct therapy for allergic rhinitis. Research indicates that bromelain can reduce nasal mucosal inflammation, nasal congestion, and related symptoms. For example, a randomized, double-blind, placebo-controlled trial published in 2012 demonstrated that bromelain supplementation led to significant improvement in symptoms and quality of life in patients with chronic rhinosinusitis, a condition with overlapping symptoms with allergic rhinitis. The enzyme is thought to modulate the immune response by reducing the release of pro-inflammatory cytokines and inhibiting the migration of neutrophils to the site of inflammation. Additionally, bromelain’s ability to break down mucus may help clear nasal passages.

However, while these effects are promising, systematic reviews note that the number of high-quality randomized controlled trials specifically targeting allergic rhinitis remains limited, and most studies combine bromelain with other therapies. The available evidence thus supports its possible benefit as an adjunct to conventional treatment but not as a stand-alone therapy. The safety profile of bromelain is generally favorable, although mild gastrointestinal side effects can occur. In summary, bromelain has a moderate level of scientific evidence supporting its use in allergic rhinitis, primarily as an adjunct to standard treatments.

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