Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the body system: Reproductive System
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Eicosapentaenoic acid (EPA), an omega-3 fatty acid found in fish oil, has some scientific evidence supporting its role in reproductive health, though the evidence is not robust and is primarily indirect. EPA is most studied for its anti-inflammatory effects and cardiovascular benefits, but its potential influence on the reproductive system is linked to modulation of inflammation, hormone synthesis, and possibly fertility outcomes. Some studies suggest that omega-3 fatty acids, including EPA, may improve endometrial receptivity and menstrual regularity, particularly in women with polycystic ovary syndrome (PCOS). For example, small clinical trials have reported improvements in ovulatory function and reductions in inflammation markers in women with reproductive disorders who supplement with omega-3s. In males, there is preliminary evidence that EPA may improve sperm quality parameters, such as motility and morphology, potentially via its anti-inflammatory and membrane-modifying effects. However, most clinical studies use mixtures of EPA and DHA, making it difficult to isolate EPA's specific effects. Large, well-controlled trials are lacking, and current reproductive health guidelines do not specifically endorse EPA supplementation for fertility or reproductive support. Thus, while there is some scientific rationale and early data suggesting a benefit, the overall evidence is limited and does not provide strong clinical validation.
More about EPA (eicosapentaenoic acid)
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acetyl l-carnitineamino acids
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beta-sitosterol
black cohosh
bovine
bovine liver
broccoli
calcium
chaste tree
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choline
coenzyme Q10 (CoQ10)
turmeric
damiana
DHA (docosahexaeonic acid)
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
fennel
fenugreek
fish protein
flaxseed
folate
gamma linolenic acid (GLA)
ginger
ginseng
gokhru
hops
inositol
iodine
iron
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-arginine
l-carnitine
lactobacillus crispatus
lactobacillus jensenii
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lignans
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melatonin
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omega-3 fatty acids
omega-6 fatty acids
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protein
pumpkin
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selenium
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vitamin D
vitamin E
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seaweed
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suma
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trace minerals
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Boerhavia diffusa
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Curculigo orchicides
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Eicosapentaenoic Acid
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yohimbine
Other body systems supported by EPA (eicosapentaenoic acid)
ArteriesBlood
Brain
Circulatory System
Eyes
Heart
Immune System
Intestinal System
Joints
Liver
Lungs
Prostaglandins
Reproductive System
Respiratory System
Skin