Evidence supporting the use of: Nettle
For the body system: Prostate

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Nettle (Urtica dioica) is commonly used to support prostate health, particularly in the context of benign prostatic hyperplasia (BPH). Scientifically, several clinical trials and studies have examined nettle root extract for its effects on lower urinary tract symptoms associated with BPH. The proposed mechanisms include inhibition of sex hormone-binding globulin, interference with aromatase activity, and anti-inflammatory effects. Randomized controlled trials have shown that nettle root, either alone or in combination with other herbal extracts (notably saw palmetto), can moderately improve urinary flow and decrease post-void residual urine in men with BPH.

Systematic reviews and meta-analyses, such as those published in "Phytomedicine" (2016) and the "Cochrane Database," indicate that while the evidence is not as robust as for pharmaceutical options, nettle root demonstrates statistically significant efficacy compared to placebo for symptom relief in BPH, though long-term safety data are limited. Traditional use also supports nettle for urinary complaints, but the scientific validation—especially for nettle root—has been growing over the past two decades. The evidence level is rated as 3 due to the presence of moderate-quality RCTs, but lack of large-scale or long-term studies prevents a higher score.

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