Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Magnesium is sometimes suggested to support the "progesterone body system," particularly in the context of reproductive health and hormone balance. Scientific evidence does not directly show that magnesium increases progesterone levels; however, magnesium plays important roles in overall reproductive health and endocrine function. Magnesium is involved in steroid hormone biosynthesis, which includes progesterone, and is necessary for the enzymatic conversions that produce these hormones. Some small studies and reviews indicate that adequate magnesium status may help reduce symptoms of premenstrual syndrome (PMS), such as mood swings and cramps, which are often associated with changes in progesterone levels during the menstrual cycle. Furthermore, magnesium deficiency has been observed in women with PMS, and supplementation has shown modest benefits in symptom reduction. However, the evidence connecting magnesium supplementation to a direct and significant increase in progesterone levels is weak and indirect. The use of magnesium for this purpose is therefore somewhat scientifically plausible but not robustly supported. The most credible support is for general reproductive health and PMS symptom relief, not specifically for boosting progesterone. More high-quality clinical research is needed to clarify magnesium’s direct effect on progesterone production.

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