Evidence supporting the use of: Relora® (proprietary)
For the health condition: PMS (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Relora® is a proprietary blend of extracts from Magnolia officinalis and Phellodendron amurense. Its primary marketed use relates to stress reduction, anxiety, and possibly the regulation of cortisol levels. While Relora® is not traditionally used for PMS (premenstrual syndrome) in herbal medicine, some recent clinical studies have explored its potential benefits for PMS symptoms, mainly due to its effects on mood and stress.
A small number of randomized, placebo-controlled trials and open-label studies suggest Relora® may reduce stress, anxiety, and irritability—symptoms that can be prominent in PMS. One pilot study found that women taking Relora® reported reductions in negative mood, anxiety, and stress compared to placebo, which could indirectly benefit PMS sufferers. However, direct studies specifically targeting PMS symptoms are very limited, and most research focuses on general stress or mood improvement rather than the full spectrum of PMS symptoms (such as bloating, breast tenderness, or specific menstrual pain).
Overall, the evidence supporting Relora® for PMS is preliminary and based on its ability to address some mood-related symptoms common to PMS, rather than robust, direct clinical validation for the full range of PMS symptoms. More and larger trials are needed to establish its effectiveness specifically for PMS. Currently, the use of Relora® for PMS is justified more by early scientific interest and indirect findings than by traditional use or strong clinical validation.
Other ingredients used for PMS (general)
27-deoxyacteinAerva lanata
Agnuside
Agrimonia pilosa
Alchemilla
Ashoka
ashwagandha
banana
bee pollen
beet
black cohosh
borage
borage oil
bupleurum falcatum
calcium
Calendula
chamomile
chaste tree
chocolate
Clary sage
Cnidium
cohosh
Cyathula
DIM (diindolylmethane)
dong quai
dong quai root
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
equol (proprietary)
estrogen
evening primrose oil
evening primrose oil
Evodia
fennel
flaxseed
gamma linolenic acid (GLA)
green tea
Gugglesterone
inositol
jujube
kudzu
Labisia pumila
Lady's Mantle
licorice root
lignans
liquid liver fractions
lotus
maca
macaenes
magnesium
Miroestrol
Montanoa tomentosa
Motherwort
peach
Phthalides
Phytoestrogens
Pimpinella
pollen
Pulsatilla
Pycnogenol
quail egg
relora® (proprietary)
royal jelly
Rubiaceae
Rubus
sage
Soy
soybean
Sweet Bay
Sweet Orange alcohol
Szechuan lovage
Valerian root
Vervain
vitamin B6
vitamin C
vitamin D
Vitex Agnus-Castus
Watermelon
Wild yam
Zinc
Other health conditions supported by relora® (proprietary)
Adrenal FatigueAnxiety
Anxiety Disorders
Appetite (excessive)
Fatigue
Irritability
Mood Swings
PMS (general)
Stress
Sugar Cravings
Worry
Products containing relora® (proprietary)
Nature's Sunshine Cortisol Formula (Nature's Cortisol Formula)
