Evidence supporting the use of: L-theanine
For the health condition: Pets (supplements for)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-theanine, an amino acid naturally found in tea leaves, is increasingly used in pet supplements, particularly for dogs and cats, to help manage stress and anxiety-related behaviors. Scientific evidence supporting its use in pets is growing but remains moderate in quality and quantity. Several studies have investigated the effects of L-theanine in animals, focusing mainly on its ability to modulate neurotransmitters such as GABA, serotonin, and dopamine, which are associated with relaxation and mood stabilization.

In dogs, clinical trials (e.g., Kato et al., 2012) have shown that L-theanine supplementation may reduce stress-related behaviors, such as barking, pacing, and destructive actions, especially during situations like separation or loud noises (fireworks, thunderstorms). Some studies have also reported modest improvements in anxiety scores when L-theanine is administered over several weeks. In cats, evidence is more limited, but some preliminary research and case reports suggest a similar calming effect.

The mechanism is thought to mirror that observed in humans: L-theanine crosses the blood-brain barrier and exerts anxiolytic effects without causing sedation. While the results are promising, the evidence is not yet robust, as sample sizes are often small and methodologies vary. Nevertheless, L-theanine is considered safe for pets at recommended doses and is commonly included in veterinary behavioral supplements. Its use is thus scientifically motivated, but more large-scale, controlled studies are needed to firmly establish efficacy.

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