Evidence supporting the use of: Magnesium
For the health condition: Pain (general remedies for)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Magnesium has been studied for its role in pain management, particularly in the context of chronic pain syndromes, migraine, and neuropathic pain. Scientific interest in magnesium stems from its role as a natural calcium antagonist and as a modulator of NMDA (N-methyl-D-aspartate) receptors, which are involved in pain transmission and central sensitization. Intravenous magnesium sulfate has been investigated for acute migraine attacks and postoperative pain, with some studies suggesting modest benefit in reducing pain intensity and opioid requirements. In chronic pain conditions such as fibromyalgia and neuropathic pain, data are mixed, with some small clinical trials and observational studies reporting symptom improvement, while others fail to show significant effects.
Overall, the evidence supporting magnesium’s use in general pain management is limited and inconsistent. Most studies are small, heterogeneous in design, and often lack rigorous controls. The strongest support exists for specific conditions like migraine and neuropathic pain rather than for general pain relief. Magnesium supplementation is generally considered safe when used appropriately, making it a low-risk adjunct in some individuals, especially those with documented deficiency. However, current clinical guidelines do not recommend magnesium as a first-line treatment for general pain, and more large-scale, high-quality studies are needed to clarify its efficacy and optimal use.
Other ingredients used for Pain (general remedies for)
allspicealpha-pinene
arjun tree
ashwagandha
waterhyssop
bamboo
barberry
myrobalan
benegut perilla (proprietary)
beta caryophyllene
beta-pinene
betel
bisabolol
black pepper
radish
Indian frankincense
bromelain
bupleurum falcatum
burdock
cabbage leaf
California poppy
camu camu
cassia bark
celery
chen pi
cherry
Chinese salvia root
chymotrypsin
cissus quadrangularis
collagen
cordyceps
turmeric
curcumin
devil's claw
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
dog rose
ethanol
fennel
fenugreek
flaxseed
fruit blend (proprietary)
gelatin
ginger
gooseberry
gotu kola
honeysuckle
Japanese sophora
jujube
kudzu
l-phenylalanine
lovage
magnesium
methylsulfonylmethane (MSM)
mint
nettle
spruce
okra
orange
peppermint oil
perilla
polygala root
protease
pumpkin
quail egg
reishi mushroom
rose oil
rutin
saffron
sage
black ginger
specialized pro-resolving mediators (SPMs)
strawberry
vitamin D
watercress
mulberry
white willow
zhejiang fritillary
sarsaparilla
yellow root
boneset
catnip
typhonium
hyssop
cardamom
atractylodes
alpinia galangal
clerodendrum indicum
hedychium spicatum
inula racemosa
anise
pistacia integerrima gall
paederia foetida
smilax
fumaria parviflora
rubia cordifolia
swertia
chaff flower
lingusticum wallichii
goldenrod
yarrow
prickly ash
morus
root tuber
silk tree
haliotis
juniper berries
solomon's seal
amber
flowering quince
cistanche
dioscorea
teasel
sweetgums
lotus seed
birch
queen of the meadow
anemarrhena asphodeloides
purslane
yucca
barrenwort
wintergreen
camphor oil
aster root
gentiana macrophylla
shepherd's purse
yerba mate
fungal enzymes blend (proprietary)
peach
noni
wood betony
biota seed
white oak
abies spectabilis
Sichuan pepper
soursop
geranium
arnica
clematis
sea salt
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alcohol
Aralia
Arjuna
akebia
Antler
Agastache
Alseodaphne andersonii
Angel's Trumpet
Aquilegia viridiflora
Alpha-Humulene
Alpha-terpineol
Agrimony
Antrodia camphorata
Achyranthes
Auricularia
Abrus
Alchornea
American Pawpaw
Amomum
Asarum heterotropoides
Albizia
Alchemilla
Aconite
Asafoetida
Ajuga
Aucubin
Andrographolide
Anserina
Agmatine
Aerva lanata
Agarwood
American Liverleaf
Anemone
Aquilegia formosa
Asam gelugor
Angostura
Andrographis
Alsonia scholaris
Actaea spicata
Agonandra
Agrimonia pilosa
Acetylsalicylic acid
Acer Truncatum bunge
Arjunic Acid
allyl isothiocyanate
Aspen
Ashoka
Argan nut oil
Asarabacca
Abuta
Alstonia macrophylla
Amor seco
Arani
Arisaema
Atractylone
Betony
Baikal Skullcap
Blue Flag
Bryonia
Baliospermum
Black spruce
Blackthorn
Bleeding Heart
Bulnesia sarmientoi
bergenin
Blubber oil
Breadnut
Blepharis
Boswellic Acid
Bistort
Baccharis dracunculifolia
Barleria
Berberis (unspecified)
Bougainvillea
Brazillian peppertree
Bugbane
Bisabolene
Benfotiamine
Bael
Butternut
Bogbean
Black Gram
Bauhinia
Boswellia
Bethroot
Banyan
Black willow
Ba Ji Tian
Barbasco
Barbary matrimony vine
Borassus aethiopum
Borage
Black root
Baobab
Bupleurum
Bittersweet
Bassia scoparia
Burning Bush
Black Hellebore
Bee venom
Bergenia
Bottle gourd
Cumin
Centella triterpenes
Calendula
Casearia esculenta
Common Monkey Flower
Chinese Mountain Ant
California Redbud
Calotropis gigantea
Carrapicho
Cucurbita
Codonopsis
Cnidium
Clerodendrum phlomidis
Cactus
Cynomorium
Cinquefoil
Cyathula
Citron
Cashew
Chinese Fleeceflower
Cymbidium goeringii
Cannabinol
Cramp Bark
Chinese Pond Turtle
Cajuput
Chuchuhuasi
Cymbopogon Martini
Centella asiatica
Coca
Capers
Celandine
Cinnamic Acid
Ceylon Leadwort
Cetylated Fatty Acids
Cissus sicyoides
Chinese Ligustrum berry
Campylandra fimbriata
Chenopodium
Chilean Wildnut
Cistus
Corktree
Cubeb
cypress
Cowslip
Cranesbill
Crinum latifolium
Chaenomeles lagenaria
Cannabidiol
Carlina
Calamus
Cherimoya
Cyanthillium cinereum
Corydalis
Cynodon dactylon
Chiococca alba
Collinsonia
Celastrus
Copaiba Oil
Colocynth
cola nut
Cynanchum
California False Hellebore
Cupuacu
Casearia sylvestris
Culvers Root
Currant
Calycophyllum
Cannabidiolic acid
Dimorphandra mollis
D-phenylalanine
Didymocarpus
Dendrobine
DIVI-DIVI
Dicentra formosa
Danshen
Dense Fruit Dittany
Deer Root
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
Dill
Dianthrone
Dwarf Morning Glory
Dolichos
Dimethyl sulfoxide (DMSO)
Dimorphandra gardneriana
Dipsacus
Dodeca-2E, 4E, 8Z, 10Z/Etetraenoic Acid Isobutylamide
European Elder
Erythropalum scandens
Erigeron
English Horsemint
Erythrina
Elk antler
Emblicanin
Emu Oil
Echinodorus
Enzyme Blend
Eupatorium
Elemi
Embelia
Eugenol
Fig
Goldthread
Lotus
Lily
Mistletoe
Mimosa
Oak
Orchid
Poppy
Rose
Spikenard
Snakeroot (unspecified)
Sweet Orange alcohol
Vervain
walnut
Other health conditions supported by magnesium
Abdominal PainAbscesses
Acid Indigestion
Addictions (drugs)
Addictions (general remedies for)
Adrenal Fatigue
Aging (prevention)
Alcoholism
Alkalosis
Allergies (respiratory)
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Autoimmune Disorders
Backache
Bipolar Mood Disorder
Birth Control (countering side effects)
Body Building
Body Odor
Boils
Broken Bones
Bronchitis
Bulimia
Calcium Deficiency
Calcium Deposits
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiac Arrest
Cardiovascular Disease
Chest Pain
Cholesterol (high)
Circulation (poor)
Colon (atonic)
Constipation (adults)
Convulsions
Cramps (leg)
Cramps (menstrual)
Cramps and Spasms
Depression
Diabetes
Digestion (poor)
Dizziness
Dysmenorrhea
Emotional Sensitivity
Endurance (lack of)
Energy (lack of)
Epilepsy
Exercise
Fatigue
Fibromyalgia Syndrome
Gastritis
Headache (cluster)
Headache (general)
Headache (tension)
Hearing Loss
Heart (weakness)
Heart Fibrillation or Palpitations
Hypertension
Insomnia
Mental Illness
Migraine
Mood Swings
Muscle Tone (lack of)
Nerve Damage
Nervous Exhaustion
Nervousness
Neurosis
Numbness
Osteoporosis
Oxygen Deficiency
Pain (general remedies for)
Paralysis
Pets (supplements for)
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
Post Partum Depression
Post Partum Weakness
Post Traumatic Stress Disorder
Pregnancy (herbs and supplements for)
Progesterone (low)
Psoriasis
Restless Leg Syndrome
Rhinitis
Seasonal Affective Disorder
Seizures
Senility
Shock
Skin (dry and/or flaky)
Skin Care (general)
Sleep (restless and disturbed)
Stress
Sugar Cravings
Surgery (healing from)
Surgery (preparation for)
Tachycardia
Tension
Testosterone (low)
Tetanus
Thinking (cloudy)
Tics
Tinnitus
TMJ
Tooth Decay
Toxemia
Triglycerides (high)
Twitching
Wasting
Wheezing
Worry
Wounds and Sores
Products containing magnesium
Nature's Sunshine CleanStart Mild
Nature's Sunshine Adrenal Support
Nature's Sunshine AIVIA Hydrate
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Plant Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AIVIA Whey Protein
Nature's Sunshine AnxiousLess
Nature's Sunshine AnxiousLess
Nature's Sunshine Calcium-Magnesium (SynerPro)
Nature's Sunshine Calcium Plus Vitamin D
Nature's Sunshine Cellular Energy
Nature's Sunshine Chromium-GTF
Nature's Sunshine Coral Calcium
Nature's Sunshine Coral Calcium
Nature's Sunshine Fibralgia
Nature's Sunshine Free Amino Acids
Nature's Sunshine Gentle Move
Nature's Sunshine Glandular System
Nature's Sunshine Heavy Metal Detox
Nature's Sunshine Magnesium
Nature's Sunshine Magnesium Complex
Nature's Sunshine Mega-Chel
Nature's Sunshine Mind-Max
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine Natural Changes
Nature's Sunshine Nature's Prenatal
Nature's Sunshine Power Beets Pouch
Nature's Sunshine Power Beets To-Go Packs
Nature's Sunshine Sea Calcium (Nature's)
Nature's Sunshine Sunshine Heroes Whole Food Papayazyme
Nature's Sunshine Silver Shield BioGuard Hand & Body Cream
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Revive
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Urinary Maintenance
Nature's Sunshine Urinary System
Nature's Sunshine VitaWave
