Evidence supporting the use of: Relora® (proprietary)
For the health condition: Mood Swings
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Relora® is a proprietary blend of extracts from Magnolia officinalis and Phellodendron amurense, marketed primarily as a dietary supplement to reduce stress and support mood balance. The rationale for its use in mood swings is based on its purported ability to regulate cortisol levels and modulate stress responses. Several small-scale clinical studies and animal research suggest that Relora® may help reduce perceived stress, anxiety, and transitory mood disturbances. For example, a randomized controlled trial published in the Journal of the International Society of Sports Nutrition (2008) found that Relora® supplementation reduced cortisol exposure and improved mood state in moderately stressed subjects. Other studies have reported similar reductions in anxiety and improvements in subjective well-being.
However, evidence specifically addressing mood swings—as distinct from general mood, stress, or anxiety—is limited. Most studies focus on stress or anxiety outcomes, and sample sizes are often small, with short study durations. There is a lack of large, high-quality, long-term clinical trials directly evaluating Relora® for mood swings in diverse populations or in those with clinically diagnosed mood disorders. Thus, while there is some preliminary scientific support for Relora® in promoting mood balance and reducing stress, the direct evidence for its effectiveness in managing mood swings is modest and warrants further research.
Other ingredients used for Mood Swings
5-Hydroxytryptophan (5-HTP)ashwagandha
beta caryophyllene
bifidobacterium longum
black tea
chaste tree
turmeric
l-theanine
l-tryptophan
l-tyrosine
lactobacillus casei
lactobacillus reuteri
licorice root
lion's mane
lithium orotate
maca
magnesium
matcha
Acetyl-L-Tyrosine
pregnenolone
reishi mushroom
relora® (proprietary)
rhodiola
vitamin B12
vitamin B6
vitamin D
zinc
St. John's Wort
yerba mate
cocoa
Bifidobacteria
bacoside
Chocolate
Devil's Club
Rose
Other health conditions supported by relora® (proprietary)
Adrenal FatigueAnxiety
Anxiety Disorders
Appetite (excessive)
Fatigue
Irritability
Mood Swings
PMS (general)
Stress
Sugar Cravings
Worry
Products containing relora® (proprietary)
Nature's Sunshine Cortisol Formula (Nature's Cortisol Formula)