Evidence supporting the use of: Szechuan lovage
For the health condition: Menstrual Irregularity

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ligusticum wallichii (commonly known as Chuanxiong or Szechuan lovage) is a well-known herb in Traditional Chinese Medicine (TCM). Its use for menstrual irregularities is primarily rooted in traditional practices rather than robust scientific evidence. In TCM, Ligusticum wallichii is believed to "invigorate the blood," "dispel wind," and "promote the movement of qi," which are thought to help regulate menstrual cycles, alleviate dysmenorrhea (painful menstruation), and address amenorrhea (absence of menstruation). The herb is often prescribed in combination with other botanicals in formulas such as Dang Gui Shao Yao San and Xue Fu Zhu Yu Tang, both of which are used for various gynecological disorders.

Although some modern pharmacological studies have explored the bioactive components of Ligusticum wallichii—such as ligustilide—and their potential effects on blood circulation and uterine smooth muscle, high-quality clinical studies directly supporting its efficacy for menstrual irregularity are limited. Most evidence comes from in vitro or animal studies, with only a few small-scale clinical trials, often with methodological limitations and usually in combination with other herbs. Therefore, while the herb’s use is deeply rooted in traditional practice and supported by centuries of empirical use, scientific validation remains limited. The overall rating for evidence supporting its use in menstrual irregularity is moderate at best, largely due to its historical rather than scientifically proven efficacy.

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