Evidence supporting the use of: Dong quai root
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Dong quai (Angelica sinensis) is a traditional Chinese medicinal root long used in Eastern medicine, particularly for women’s health issues. Its use as a treatment for menopause symptoms is primarily rooted in traditional practices. Dong quai is often referred to as "female ginseng" and has been used for centuries in China, Korea, and Japan to alleviate symptoms such as hot flashes, night sweats, and mood swings associated with menopause. It is commonly included in herbal formulas such as Toki-shakuyaku-san and Dang Gui Liu Huang Tang.

Scientific evidence for dong quai's efficacy in treating menopausal symptoms is limited and mixed. Some laboratory studies suggest that dong quai contains phytoestrogenic compounds, which might theoretically help balance estrogen levels during menopause. However, clinical trials in humans have generally not demonstrated significant benefit. For example, a well-known randomized controlled trial published in JAMA (2001) found that dong quai was no more effective than placebo for hot flashes.

In summary, while dong quai is widely used in traditional medicine for menopause support, robust clinical evidence is lacking. Most reputable organizations and reviews conclude that more research is needed before dong quai can be recommended for menopause. Possible side effects and drug interactions should also be considered.

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