Evidence supporting the use of: Bupleurum falcatum
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Bupleurum falcatum is an herb with a long history of use in traditional Chinese medicine (TCM), primarily as part of multi-herb formulas such as Xiao Yao San (Free and Easy Wanderer). In TCM, it is used to harmonize the liver and support overall balance, including symptoms associated with menopause such as mood swings, irritability, and hot flashes. However, its use for menopause is based almost entirely on traditional practice rather than direct scientific study. There is a lack of robust clinical evidence specifically evaluating Bupleurum falcatum for menopausal symptoms. Most available research has focused on its anti-inflammatory, hepatoprotective, and immunomodulatory effects, rather than on hormonal or menopausal outcomes. The rationale for including Bupleurum falcatum in menopause-supporting formulas is rooted in the TCM approach, which addresses imbalances believed to underlie menopausal complaints. While some animal studies suggest potential neuroprotective and mood-regulating properties, these have not been adequately tested in clinical trials involving menopausal women. Therefore, while traditional use supports its inclusion for menopause-related symptoms, direct scientific validation remains minimal, and the overall level of evidence should be considered low.

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Other ingredients used for Menopause

7-hydroxymatairesinol (HMR)
Alfalfa
Aloe vera
ashwagandha
asparagus
astragalus
black cohosh
black currant
Indian frankincense
bupleurum falcatum
burdock
calcium
chaste tree
cordyceps
damiana
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dog rose
dong quai root
eleuthero
evening primrose oil
fenugreek
fish oil
flaxseed
genistein
genistin
hibiscus
HMR lignan
hops
knotweed
jujube
kudzu
licorice root
lignans
maca
Marine lipid
Melatonin
Moringa
Motherwort
Nettle
okra
omega-3 fatty acids
ophiopogon root
pollen
pomegranate
rehmannia glutinosa
reishi mushroom
rose oil
saffron
sage
soybean
Valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
seaweed
Wild yam
red clover
atractylodes
smilax
Rubia cordifolia
bee pollen
lingzhi
root tuber
dioscorea
royal jelly
equol (proprietary)
anemarrhena asphodeloides
barrenwort
goji berry
amaranth
soy isoflavones
27-deoxyactein
8-Prenylnaringenin
Akebia
antler
Achyranthes
Alchemilla
Agrimonia pilosa
Agnuside
Ashoka
Anemarrhena
atractylone
black seed
banyan
bioflavonoids
black root
Chinese silkvine
cohosh
Clary sage
Cnidium
Cynomorium
Crinum latifolium
DHEA
danshen
daidzein
durian
dong quai
Euryale seed
elk antler
evening primrose oil
estrogen
fo-ti
Ficus religiosa
Glycetein
horny goat weed
Hypericum
isoflavones
Lycium
lemon balm
Lady's Mantle
linden
lotus
Loranthus
Labisia pumila
macamides
Montanoa tomentosa
Meadow sage
Miroestrol
macaenes
Ophiopogon
Puerain
Pulsatilla
Prickly Pear Cactus
Phytoestrogens
Polygonum
rue
Rubus
rockweed
Rehmannia
rose
Rooibos
Rosa laevigata
rhubarb
Soy
Soy Protein
Stone Root
Vervain
Viburnum
Vitex Agnus-Castus
Withanolides
Yellow-Fruit Nightshade