Evidence supporting the use of: Cat's claw
For the health condition: Lupus

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Cat's claw (Uncaria tomentosa) is a climbing vine native to the Amazon and other areas of Central and South America. Its traditional use traces back to indigenous Amazonian cultures, who have employed it for centuries as a remedy for inflammation, arthritis, and various chronic illnesses. While it is popularly marketed as an herbal supplement for immune modulation and inflammatory conditions, including autoimmune diseases like lupus (systemic lupus erythematosus), the foundation for its use in lupus is primarily traditional rather than scientific.

The rationale behind its use is based on cat's claw's documented anti-inflammatory and immunomodulatory properties in laboratory and some animal studies. These studies suggest potential benefits in reducing pro-inflammatory cytokines and modulating immune function. However, clinical trials specifically investigating the safety and efficacy of cat's claw in people with lupus are lacking. Only limited human studies exist—mainly in the context of osteoarthritis or general immune support, not lupus. Furthermore, because lupus is an autoimmune disease where immune system overactivity is a problem, immunostimulant herbs like cat's claw could theoretically worsen symptoms in some individuals.

In summary, while cat's claw is traditionally used for inflammatory disorders and is sometimes recommended for lupus based on its general anti-inflammatory reputation, high-quality scientific evidence supporting its safe and effective use for lupus is minimal. Anyone considering cat's claw for lupus should consult a healthcare professional, as herbal supplements can interact with medications and may not be appropriate for all autoimmune conditions.

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