Evidence supporting the use of: Zinc
For the health condition: Leaky Gut Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Zinc is used to support or treat Leaky Gut Syndrome based on emerging scientific evidence. Leaky Gut Syndrome, characterized by increased intestinal permeability, has been associated with various gastrointestinal and systemic conditions. Zinc plays a crucial role in maintaining the integrity of the intestinal mucosal barrier. Several studies have shown that zinc supplementation can help restore and maintain tight junctions between intestinal epithelial cells, thereby reducing permeability. For example, research published in Gut (2001) demonstrated that zinc supplementation reduced gut permeability in patients with Crohn’s disease. Similarly, animal studies have indicated that zinc deficiency leads to impaired gut barrier function and increased inflammation, while zinc supplementation reverses these effects.

Although the concept of "Leaky Gut Syndrome" as a distinct clinical diagnosis remains controversial, the role of zinc in gut health is supported by mechanistic and clinical studies, particularly in the context of intestinal inflammation and injury. However, most of the evidence comes from studies on specific diseases (e.g., Crohn’s disease, diarrhea, and critical illness) rather than on "Leaky Gut Syndrome" per se. Therefore, while there is a scientific basis for using zinc to support gut barrier function, more high-quality, targeted clinical trials are needed to confirm its efficacy specifically for Leaky Gut Syndrome in the general population.

More about zinc
More about Leaky Gut Syndrome

Other health conditions supported by zinc

Abrasions
Acne
Acquired Immune Deficiency Syndrome
Aging (prevention)
Alcoholism
Anemia
Anorexia
Antibiotics (alternatives to)
Anxiety
Anxiety Disorders
Appetite (deficient)
Arthritis
Athlete's Foot
Attention Deficit Disorder
Autism
Autoimmune Disorders
Benign Prostate Hyperplasia
Birth Defects (prevention)
Bites and Stings
Blisters
Body Building
Body Odor
Boils
Broken Bones
Bruises (healing)
Bulimia
Burns and Scalds
Calcium Deficiency
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiovascular Disease
Cartilage Damage
Cataracts
Celiac Disease
Cervical Dysplasia
Chemotherapy (reducing side effects)
Cholera
Cirrhosis of the Liver
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colitis
Concentration (poor)
Congestion
Congestive Heart Failure
Conjunctivitis
Contagious Diseases
Convalescence
Copper Toxicity
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cradle Cap
Cramps (menstrual)
Crohn's Disease
Cuts
Cystic Fibrosis
Dandruff
Debility
Dehydration
Depression
Dermatitis
Diabetes
Diabetic Retinopathy
Diaper Rash
Diarrhea
Digestion (poor)
Duodenal Ulcers
Dysentery
Eczema
Endometriosis
Energy (lack of)
Enteritis
Epstein Barr Virus
Erectile Dysfunction
Exercise
Eye Infections
Eye Problems
Eyes (red or itching)
Eyes (spots before)
Eyesight (poor)
Failure to Thrive
Fat Metabolism (poor)
Fatty Liver Disease
Fibrosis
Fingernails (weak or brittle)
Foot Odor
Free Radical Damage
Gastritis
Giardia
Gingivitis
Hair (loss or thinning)
Hair Care (general)
Halitosis
Hashimoto's Disease
Hearing Loss
Heart (weakness)
Heavy Metal Poisoning
Hemochromatosis
Hemorrhoids
Hepatitis
Herpes
Hypothyroid
Impetigo
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Insomnia
Irritability
Irritable Bowel Syndrome
Itching
Itching (rectal)
Jock Itch
Labor and Delivery
Lead Poisoning
Leaky Gut Syndrome
Leprosy
Lesions
Leucorrhea
Liver Detoxification
Lupus
Macular Degeneration
Mastitis
Measles
Memory and Brain Function
Menorrhagia
Menstrual Irregularity
Mental Illness
Metabolic Syndrome
Migraine
Miscarriage (prevention)
Mononucleosis
Mood Swings
Nerve Damage
Nervous Exhaustion
Night Blindness
Nursing
Obsessive Compulsive Disorder
Oral Surgery
Osteoporosis
Pancreatitis
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Pneumonia
Poison Ivy or Oak
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Premature Ejaculation
Progesterone (low)
Prostatitis
Protein Digestion (poor)
Psoriasis
Puberty (hormone balancer)
Rashes and Hives
Rhinitis
Rosacea
Scars / Scar Tissue
Schizophrenia
Scratches and Abrasions
Seborrhea
Sex Drive (low)
Shingles
Sickle Cell Anemia
Sinus Infection
Skin (dry and/or flaky)
Skin (infections)
Skin (oily)
Skin Care (general)
Sleep (restless and disturbed)
Small Intestinal Bacterial Overgrowth
Smell (loss of)
Sore or Geographic Tongue
Sore Throat
Stress
Stye
Sugar Cravings
Sunburn
Surgery (healing from)
Surgery (preparation for)
Syphilis
Teeth (loose)
Testosterone (low)
Thinking (cloudy)
Tickle in Throat
Tonsillitis
Tooth Decay
Toxemia
Triglycerides (high)
Tuberculosis
Ulcerations (external)
Ulcers
Vitiligo
Warts
Wasting
Worry
Wounds and Sores

Products containing zinc

Nature's Sunshine Love and Peas (Sugar Free)
Nature's Sunshine 5-HTP Power
Nature's Sunshine Adrenal Support
Nature's Sunshine AnxiousLess
Nature's Sunshine AnxiousLess
Nature's Sunshine Bowel Detox
Nature's Sunshine Calcium-Magnesium (SynerPro)
Nature's Sunshine Candida Clear
Nature's Sunshine Cellular Energy
Nature's Sunshine Children's Elderberry Immune
Nature's Sunshine Children's MultiVitamin & Mineral
Nature's Sunshine Defense Maintenance
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Glandular System
Nature's Sunshine Love and Peas
Nature's Sunshine Master Gland Formula®
Nature's Sunshine Mega-Chel
Nature's Sunshine Men's Formula (With Lycopene)
Nature's Sunshine MultiVitamin & Mineral (SynerPro)
Nature's Sunshine MultiVitamin & Mineral (Time Release)
Nature's Sunshine Natural Changes
Nature's Sunshine Nature's Prenatal
Nature's Sunshine Nature's Harvest
Nature's Sunshine Perfect Eyes
Nature's Sunshine Power Greens
Nature's Sunshine Power Greens To-Go
Nature's Sunshine Power Meal
Nature's Sunshine Power Meal
Nature's Sunshine Skeletal Strength
Nature's Sunshine Solstic Twenty-Four
Nature's Sunshine Solstic Immune
Nature's Sunshine Structural System (30 Day Program)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Target TS-II Formula
Nature's Sunshine Thyroid Support
Nature's Sunshine Ultrabiome DTX
Nature's Sunshine VitaWave
Nature's Sunshine Yeast/Fungal Detox
Nature's Sunshine Zinc
Nature's Sunshine Zinc Lozenge