Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Fish oil, rich in omega-3 polyunsaturated fatty acids (particularly EPA and DHA), has been explored as a supportive therapy for Inflammatory Bowel Disorders (IBD) such as Crohn’s disease and ulcerative colitis. The scientific rationale is primarily based on the anti-inflammatory properties of omega-3 fatty acids, which can modulate the production of pro-inflammatory eicosanoids, cytokines, and reactive oxygen species involved in the pathogenesis of IBD. Early observational studies and small clinical trials suggested that fish oil supplementation could reduce disease activity or maintain remission in IBD patients. However, larger randomized controlled trials (RCTs) and systematic reviews have yielded mixed results. A 2014 Cochrane Review concluded that omega-3 fatty acids were not more effective than placebo in maintaining remission in Crohn's disease, and evidence for ulcerative colitis was similarly inconclusive. Some studies have noted modest improvements in specific symptoms or biomarkers, but these benefits have not translated into consistent clinical recommendations. Overall, while the theoretical basis and some preliminary data support fish oil's use, robust, consistent clinical evidence is lacking. Therefore, fish oil is sometimes used as an adjunctive therapy, but it is not considered a primary or well-validated treatment for IBD. Patients interested in fish oil supplementation should consult with their healthcare provider to weigh potential benefits and risks.

More about fish oil
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Other ingredients used for Inflammatory Bowel Disorders

Other health conditions supported by fish oil

Products containing fish oil

Nature's Sunshine Circulatory System
Nature's Sunshine DHA
Nature's Sunshine Krill Oil (With Vitamin K2)
Nature's Sunshine Super Omega 3 EPA
Nature's Sunshine Super Omega 3 EPA
Nature's Sunshine Super Trio