Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Pau d’arco (Tabebuia species) is a tree native to South America whose inner bark has been used in traditional medicine, particularly in Brazil and other parts of the Amazon. Historically, indigenous peoples and herbal practitioners have used pau d’arco preparations—such as teas and tinctures—to address infections, including bacterial, viral, and fungal conditions. The rationale for its use comes from the presence of bioactive compounds called naphthoquinones, especially lapachol and beta-lapachone, which have been shown in laboratory studies to possess antimicrobial and antifungal properties.

However, while in vitro (test tube) studies support pau d’arco’s ability to inhibit certain pathogens, robust clinical research in humans is lacking. Most of the evidence remains anecdotal or comes from traditional use, rather than well-designed clinical trials. Some small animal studies suggest potential benefits, but doses required for antimicrobial effects may be unsafe for humans, as high doses of pau d’arco can cause side effects such as nausea, vomiting, and bleeding disorders.

In summary, although pau d’arco has a long history of traditional use for treating infections and some laboratory evidence suggests antimicrobial properties, there is insufficient clinical evidence to support its efficacy or safety for this purpose in humans. More rigorous research is needed to determine its potential role in infection management.

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Other ingredients used for Infection

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