Anamu (Petiveria alliacea) has a long history of use in traditional medicine, particularly in Central and South America and the Caribbean. It has been used for a variety of ailments, including infections and immune-related conditions. Specifically, its use for herpes is rooted in traditional practices rather than strong scientific validation. Folk medicine practitioners have employed anamu as an herbal remedy, often using it topically or as a decoction, to address viral infections such as herpes simplex virus (HSV), likely due to its perceived antiviral and immune-boosting properties.

The scientific evidence supporting anamu’s efficacy against herpes is limited. Some in vitro studies have demonstrated that extracts of Petiveria alliacea possess antiviral activity against certain viruses, but direct evidence against herpes simplex virus is sparse and mostly preliminary. The mechanisms suggested include inhibition of viral replication and modulation of immune responses, but these findings are not sufficient to recommend its use as a validated treatment for herpes in humans.

In summary, while anamu is traditionally used for herpes, the scientific evidence is weak and largely based on laboratory studies rather than clinical trials. Its use remains primarily supported by historical tradition and anecdotal reports.