Divi-divi (Caesalpinia coriaria) is a plant native to the Caribbean, Central America, and northern South America. Its pods and leaves have been used traditionally in folk medicine, primarily for their astringent properties. In some cultures, divi-divi has been employed as a remedy for a variety of ailments, including headaches. However, the documentation of this use is sparse, generally limited to anecdotal reports or mentions in ethnobotanical surveys. There are no well-documented or widely accepted traditional preparations specifically for headache relief, and divi-divi is more often cited for uses such as treating diarrhea, wounds, or skin conditions.

Scientific studies on divi-divi are limited and focus mostly on its tannin content and possible antimicrobial or antioxidant properties. There is no clinical or preclinical research validating its use for the treatment of headaches. Thus, while there is some weak traditional precedent for its use in headache (usually as a poultice or topical application), the evidence is anecdotal and not supported by rigorous scientific investigation.

In summary, divi-divi’s use for headaches is based on limited traditional knowledge, with little to no scientific backing or detailed ethnomedical records for this specific condition. Its efficacy for headache relief remains unproven.