Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Broussonetia, particularly Broussonetia papyrifera (paper mulberry), has a history of use in traditional medicine systems in East Asia. In Chinese ethnomedicine, various parts of the plant (such as leaves, bark, and roots) have been used for a range of ailments, including headache. The rationale for its use in headache is primarily based on traditional herbal practices rather than systematic clinical evaluation. Some traditional texts and herbal compendiums mention Broussonetia preparations as having analgesic, anti-inflammatory, or sedative properties, which could theoretically relieve headache symptoms. However, there is an absence of high-quality scientific studies (such as randomized controlled trials or robust pharmacological studies) specifically investigating Broussonetia’s efficacy for headache relief. Any reported effects are anecdotal or based on long-standing traditional use. Existing pharmacological research on Broussonetia focuses more on other bioactivities (e.g., antioxidant, anti-diabetic, or anti-inflammatory effects), and does not directly address headache. Therefore, the use of Broussonetia for headaches is justified by traditional rather than scientific evidence, and the overall evidence rating is low.

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