Mountain mahogany (Cercocarpus species) has a history of use in traditional Native American herbal medicine, particularly among tribes in the western United States. Historical ethnobotanical records indicate that some indigenous groups used mountain mahogany preparations for a variety of ailments, including as a wash or poultice for skin issues and inflammation, which may have included applications for swollen glands or lymph nodes. However, the evidence for its use specifically targeting the lymphatic system or swollen lymph glands is sparse and generally anecdotal. There are no modern clinical studies, pharmacological investigations, or robust scientific validations supporting its efficacy for this indication. Most of the references to its use are found in ethnobotanical surveys and do not provide detail on dosage, preparation, or mechanism of action. As such, while mountain mahogany has a place in traditional medicine, the specific use for swollen glands is weakly documented and not scientifically substantiated.