Evidence supporting the use of: Luffa
For the health condition: Glands (swollen lymph)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Luffa (also spelled loofah) is primarily recognized in traditional and folk medicine systems, especially in parts of Asia, for its purported health benefits, including its use for treating swollen glands, which generally refers to swollen lymph nodes. Historical use is documented in Traditional Chinese Medicine (TCM), where Luffa species (such as Luffa cylindrica) have been incorporated into herbal remedies for conditions described as "phlegm" or "toxin" accumulations, sometimes manifesting as swellings or nodules. The dried sponge gourd, seeds, or extracts have been formulated into decoctions or topical applications. However, these uses are based on traditional concepts rather than the modern biomedical understanding of lymphatic disease. Scientific evidence supporting the use of Luffa for swollen glands or lymphatic conditions is extremely limited. While some laboratory studies have explored anti-inflammatory or immunomodulatory effects of Luffa extracts, these are preliminary, and there is no direct clinical research validating its use for lymphadenopathy or related conditions. Therefore, the evidence rating is low (1 out of 5), and its application remains largely rooted in traditional practice rather than scientific validation. Individuals interested in using Luffa for swollen glands should consult healthcare professionals, as swollen lymph nodes can have many causes, some requiring urgent medical attention.

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