Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bupleurum is a genus of plants commonly used in traditional Chinese medicine (TCM), most notably as a primary ingredient in formulas such as Xiao Chai Hu Tang (Minor Bupleurum Decoction). Traditionally, Bupleurum has been used to "soothe the liver," "harmonize the interior and exterior," and to help manage "shaoyang disorders." In TCM, swollen lymph glands are often interpreted as manifestations of "heat-toxin" or "phlegm" syndromes, and Bupleurum-containing formulas may be prescribed to help address these patterns, especially when associated with conditions like chronic infections, fever, or inflammatory states. There is limited modern scientific evidence directly supporting Bupleurum for the treatment of swollen lymph glands. Most available research focuses on its anti-inflammatory, immunomodulatory, and hepatoprotective effects, which are largely based on animal studies or in vitro experiments. Although these properties could theoretically impact conditions involving lymphatic swelling, there are no clinical trials or robust scientific studies demonstrating efficacy of Bupleurum specifically for swollen lymph nodes or lymphadenopathy in humans. In summary, while Bupleurum has a long history of traditional use for conditions that may involve swollen glands within the context of TCM theory, current scientific validation for this specific use is minimal. Thus, its use for swollen lymph glands is justified primarily by tradition rather than solid clinical evidence.

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