Phosphate ascorbate, a buffered form of vitamin C (ascorbic acid), has been investigated for its potential role in the management of gingivitis, primarily due to vitamin C's established importance in oral and periodontal health. Vitamin C is an essential nutrient for the maintenance of healthy connective tissue, including the gums, and is involved in collagen synthesis and immune function. Deficiency in vitamin C is known to lead to scurvy, a condition characterized by bleeding gums and poor wound healing.

Several studies have explored vitamin C supplementation in the context of gingivitis, with some reporting improvements in clinical parameters such as bleeding on probing and gingival index scores, especially in individuals with low baseline vitamin C status. However, most studies focus on ascorbic acid rather than specifically phosphate ascorbate, and the evidence base remains limited and mixed. Systematic reviews and clinical guidelines generally note that while vitamin C deficiency can exacerbate gingival inflammation, routine supplementation in individuals with adequate intake does not provide significant additional benefit for gingivitis management. There is no robust, high-quality evidence that phosphate ascorbate is superior to other forms of vitamin C in this context.

In summary, while there is a biological rationale and some limited scientific evidence supporting the use of vitamin C (including phosphate ascorbate) for gingivitis, the overall strength of evidence is low, and its use should not replace established dental hygiene practices.