Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Carthamus, commonly known as safflower, has a long history of use in traditional medicine systems, particularly in Traditional Chinese Medicine (TCM). In TCM, safflower is believed to promote blood circulation and remove blood stasis, and it has been incorporated into herbal formulations intended for oral health, including the treatment of gum diseases such as gingivitis. However, this traditional use is not supported by robust modern scientific evidence. There are a few in vitro and animal studies examining the anti-inflammatory and antioxidant properties of Carthamus extracts, but direct clinical studies demonstrating efficacy in the treatment or prevention of gingivitis in humans are lacking. The rationale for its traditional use is often based on its general anti-inflammatory effects and its purported ability to improve local blood flow, which could theoretically benefit gingival tissues. Despite this, current dental and medical guidelines do not include Carthamus among recommended treatments for gingivitis, and there is a lack of high-quality randomized controlled trials to validate its effectiveness for this specific condition. In summary, while Carthamus is traditionally used for oral inflammation, there is minimal scientific validation for its efficacy in treating gingivitis.

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