Evidence supporting the use of: Amylase
For the health condition: Gas and Bloating

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Amylase is an enzyme responsible for breaking down complex carbohydrates (starches) into simpler sugars during digestion. It is naturally produced in the human body, primarily by the saliva and pancreas. Over-the-counter digestive enzyme supplements, often containing amylase, are marketed to individuals who experience digestive discomfort, including gas and bloating, especially after consuming starchy foods. The rationale behind using amylase for these symptoms is that incomplete digestion of carbohydrates can lead to fermentation by gut bacteria, producing gas and causing bloating. There is some scientific basis for this use: studies suggest that certain individuals, such as those with pancreatic insufficiency or other digestive enzyme deficiencies, may benefit from supplemental enzymes, including amylase. In these populations, enzyme supplements have been shown to reduce gastrointestinal symptoms, including bloating and flatulence. However, in healthy individuals without enzyme deficiencies, the evidence is less robust. Most clinical studies focus on broader digestive enzyme blends rather than isolated amylase, and the quality of evidence varies, with relatively few large, well-controlled studies directly linking amylase supplementation alone to reduced gas and bloating. Overall, the use of amylase for gas and bloating is scientifically plausible and supported by moderate evidence in populations with enzyme deficiencies, but the benefits for the general population remain uncertain. The strength of evidence is therefore rated as 2 out of 5.

More about amylase
More about Gas and Bloating

Other ingredients used for Gas and Bloating

activated charcoal
allspice
alpha-galactosidase
amylase
apple
artichoke
bacillus coagulans
basil
benegut perilla (proprietary)
beta-pinene
bifidobacterium bifidum
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black pepper
bасора
chamomile
chen pi
cinnamon
coating
coconut milk
cucumber
turmeric
dandelion
fennel
fenugreek
fiber blend (proprietary)
fructooligosaccharides (FOS)
gentian root
ginger
greek mountain tea
green banana
cellulase
horseradish
isomalto-oligosaccharide
quassia
lactobacillus gasseri
lemon
licorice root
lipase
lovage
mastic gum
microbial enzymes (proprietary)
mint
okra
oregano
pancreatin
parsley
pear
peppermint oil
pineapple
prebiotic blend (proprietary)
butyric acid
psyllium
raspberry
rhubarb root
sage
schizonepeta
slippery elm bark
spearmint leaf
triphala
wasabia japonica
xylanase
bentonite
cascara sagrada
tangerine
hyssop
cardamom
atractylodes
capsicum
Indian bael
neem tree
alpinia galangal
ferula assafoetida
hedychium spicatum
inula racemosa
anise
commiphora
caesalpinia crista
fumaria parviflora
goldenrod
yarrow
bile salt
prickly ash
elecampane
flowering quince
dogwood
fern
sweet flag
morinda
trichosanthes
zanthoxylum
birch
queen of the meadow
polyphenols
caraway
wintergreen
camphor oil
menthol oil
fungal enzymes blend (proprietary)
wood betony
paw paw
horehound
Sichuan pepper
alginic acid
enzymes blend (proprietary)
cayenne pepper
geranium
akebia
Apple Cider Vinegar
Actinidin
Agastache
Angelica
acacia
Agrimony
Anamu
Amomum
Asafoetida
Ajuga
Aerva lanata
American Liverleaf
Asam gelugor
Angostura
Arrowroot
Agrimonia pilosa
Antifoam agent
Bifidobacterium
Buttermilk
Blue Flag
Blackthorn
Bicarbonate
Bayleaf
Belleric myrobalan
Bran
Butea monosperma
Bitter Grass
Bael
boldo
black salt
Bifidobacterium animalis
Black Nightshade
Borassus Palm
Buddha's Hand
Borassus aethiopum
Bitter principals
Bacteria
banana
Belamcanda
Bergenia
Bottle gourd
Borneol
Cumin
Centaury
Chinese Silkvine
Cinnamomum
Carqueja
Chervil
coconut oil
Coriander
Centaurium erythraea
Cyathula
Carry Me Seed
Cajuput
Chlorophytum
Carvone
Cymbopogon Martini
Coca
Capers
Chanca Piedra
Campylandra fimbriata
Chenopodium
Colombo
Centipeda
Cubeb
Carob
Chirata
Cha de bugre
Carlina
Calamus
Cosmos
Costus
Castor Oil
Colocynth
cola nut
Clerodendrum indicum
Dianthus
Dimethylpolysiloxane
Dragonhead
Dill
Dolichos
Dichrostachys glomerata
Eupatorium
Embelia
Garlic
Galangal
Mustard
Prickly Pear Cactus
Potash
Quince
Rose
Rhubarb
Snakeroot (unspecified)
Vinegar

Other health conditions supported by amylase

Digestion (poor)
Gas and Bloating
Indigestion