Evidence supporting the use of: Milk thistle
For the health condition: Gall Bladder (sluggish or removed)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Milk thistle (Silybum marianum) has a long history of use in traditional herbal medicine for supporting liver and gallbladder health. Its primary active compound, silymarin, is thought to have hepatoprotective (liver-protecting) properties, and some traditional systems have extended this to include benefits for the gallbladder, particularly when it is sluggish or has been removed. Historically, herbalists believed that supporting the liver would indirectly aid the gallbladder due to their close physiological relationship in bile production and secretion.
However, scientific evidence specifically linking milk thistle to improved gallbladder function or outcomes after gallbladder removal is limited. Most research has focused on its effects on the liver, such as potential benefits in hepatitis or cirrhosis, with only secondary speculation about possible benefits for bile flow. A handful of animal and laboratory studies suggest silymarin may have choleretic effects (stimulating bile flow), but robust clinical trials in humans with gallbladder disorders are lacking.
In summary, the use of milk thistle for gallbladder support is primarily grounded in tradition and extrapolation from its effects on the liver. Direct scientific evidence for its efficacy in treating a sluggish or removed gallbladder is weak, and the current body of evidence would best be described as suggestive but unproven.
More about milk thistle
More about Gall Bladder (sluggish or removed)
Other ingredients used for Gall Bladder (sluggish or removed)
appleartichoke
barberry
beet
bovine
bupleurum falcatum
burdock
chicory
turmeric
dandelion
ginger
horseradish
lemon
licorice root
lipase
milk thistle
mustard seed
oregon grape
ox bile
pancreatin
parsley
pear
phellodendron amurense
phosphatidylcholine
silymarin
triphala
atractylodes
papaya
Indian bael
punarnava
fumaria parviflora
peony
goldenrod
bile salt
myrrh
cornsilk
birch
couch grass
cleavers
enzymes blend (proprietary)
Avens
Angelica
American Liverleaf
Brassica
Berberis (unspecified)
Bitter Grass
boldo
Baccharoides anthelmintica
Bur-Reed
Bile
Black Nightshade
Bitter principals
bile acid
Bupleurum
Boerhavia diffusa
cholic acid
Carqueja
Cynarin
Costus
Castor Oil
Colocynth
Dianthus
Duodenal Substance
Dehydrocholic acid
Endive
Other health conditions supported by milk thistle
Abdominal PainAddictions (general remedies for)
Alcoholism
Cancer Treatment (reducing side effects)
Chemical Poisoning
Chemotherapy (reducing side effects)
Cirrhosis of the Liver
Environmental Pollution
Fat Metabolism (poor)
Fatty Liver Disease
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Hangover
Heavy Metal Poisoning
Hepatitis
Jaundice (adults)
Liver Detoxification
Poisoning (general)
Products containing milk thistle
Nature's Sunshine CleanStart Mild
Nature's Sunshine Detox Basics (Best used by 7/31/25)
Nature's Sunshine Dieter's Cleanse
Nature's Sunshine Enviro-Detox
Nature's Sunshine Heavy Metal Detox
Nature's Sunshine Hepatic System
Nature's Sunshine Milk Thistle Combination
Nature's Sunshine Milk Thistle (Time Release)
Nature's Sunshine Super Antioxidant