Evidence supporting the use of: Caprylic acid
For the health condition: Fungal Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Caprylic acid, a medium-chain fatty acid found in coconut oil and palm kernel oil, has been studied for its antifungal properties, particularly against Candida species. The scientific basis for its use lies in in vitro research, where caprylic acid demonstrates the ability to disrupt fungal cell membranes, leading to cell death. Several laboratory studies have shown that caprylic acid can inhibit the growth of various Candida species, which are common causes of fungal infections in humans.

However, while the antifungal effects are clear in petri dish experiments, clinical evidence in humans is limited. Few small studies and anecdotal reports suggest that orally administered or topically applied caprylic acid may help reduce symptoms of fungal overgrowth, but no large-scale, well-controlled clinical trials have confirmed its effectiveness for treating fungal infections. Most of the available human data come from studies of combined supplements or dietary strategies rather than isolated caprylic acid.

Overall, caprylic acid's use for fungal infections is supported by laboratory studies and some early clinical observations, but robust human trials are lacking. Therefore, the evidence rating is moderate to low (2 out of 5), indicating that while there is a plausible scientific mechanism and some preliminary support, more rigorous research is needed to conclusively establish its efficacy for treating fungal infections in humans.

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