Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Neem (Azadirachta indica) has a long history of use in traditional medicine systems, particularly Ayurveda, for managing fever. In traditional Ayurvedic texts, neem leaves, bark, and extracts have been described as remedies to "cool" the body and reduce fever, often attributed to their supposed detoxifying and antimicrobial properties. Neem is sometimes used in decoctions or teas for this purpose, either alone or combined with other herbs. However, while there is some preclinical evidence suggesting neem’s bioactive compounds possess antipyretic (fever-reducing) effects in animal studies, robust clinical evidence in humans is lacking. Most scientific studies remain preliminary, with small sample sizes, unclear methodologies, or results limited to animal models (such as rats treated with neem extracts showing reduced experimentally induced fever). Therefore, the use of neem for fever is primarily justified by traditional, historical practices rather than strong scientific validation. It is important to note that fever can be a symptom of various underlying conditions, and self-treating with neem in place of proven medical therapies is not recommended. More rigorous clinical trials are needed to substantiate neem’s effectiveness and safety for fever management in humans.

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