Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Chenopodium oil, derived from the seeds of Chenopodium ambrosioides (commonly known as American wormseed or epazote), has a long history of traditional use in various medicinal systems, particularly in Central and South America. Its primary historical application has been as an anthelmintic (to expel intestinal worms), but there are ethnobotanical records that indicate occasional use as a remedy for fever. This usage appears in some folk medicine practices, where Chenopodium preparations were given for symptomatic relief during febrile illnesses, likely owing to its perceived general medicinal properties rather than targeted antipyretic effects.

However, there is very limited scientific research specifically validating the effectiveness of Chenopodium oil for treating fever. The oil contains active components such as ascaridole, which has notable biological activity, but the available research focuses on antiparasitic properties rather than antipyretic (fever-reducing) effects. No controlled clinical trials or robust pharmacological studies have demonstrated a direct fever-reducing action of Chenopodium oil. Moreover, the oil can be toxic if improperly used, which limits its safety profile for such indications.

In summary, the use of Chenopodium oil for fever is primarily supported by traditional anecdotal evidence rather than scientific validation, and the overall quality of evidence supporting this application is low.

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